Intermittent fasting may impart metabolic benefits independent of energy balance by
initiating fasting-mediated mechanisms. This randomized controlled trial examined 24-hour …

Simple Summary Reduced food intake significantly enhances healthy lifespan in both model
animals and humans, and decreases the incidence of cancer and other age-related …

Human trials that compare intermittent fasting (IF) to calorie restriction (CR) with
psychological, behavioral and cognition outcomes are limited. We hypothesized that there …

Physiological adaptations to intentional weight loss can facilitate weight regain. This review
summarizes emerging findings on hypothalamic and brainstem circuitry in the regulation of …

There is substantial overlap in risk factors for the pathogenesis and progression of breast
cancer (BC) and cardiovascular disease (CVD), including obesity, metabolic disturbances …

The primary objective of this study was to compare weight changes in two groups of ageing
Irish adults with overweight and adiposity-based chronic disease: participants who had …

Understanding physiological and behavioral responses to energy imbalances is important
for the management of overweight/obesity and undernutrition. Changes in body composition …

Background Although over one hundred equations have been developed to predict the
energy expenditure of individuals, none are sensitive to weight change in assessment of …

Background: Engaging in sufficient levels of physical activity, guarding against sustained
sitting, and maintaining a healthy body weight represent important lifestyle strategies for …

New Findings What is the central question of this study? How does intrinsic aerobic capacity
impact weight loss with 50% daily caloric restriction and alternate‐day fasting? What is the …