Analgesic potential of terpenes derived from Cannabis sativa
E Liktor-Busa, A Keresztes, J LaVigne… - Pharmacological …, 2021 - ASPET
Pain prevalence among adults in the United States has increased 25% over the past two
decades, resulting in high health-care costs and impacts to patient quality of life. In the last …
decades, resulting in high health-care costs and impacts to patient quality of life. In the last …
[HTML][HTML] Cannabis: a toxin-producing plant with potential therapeutic uses
For thousands of years, Cannabis sativa has been utilized as a medicine and for
recreational and spiritual purposes. Phytocannabinoids are a family of compounds that are …
recreational and spiritual purposes. Phytocannabinoids are a family of compounds that are …
[HTML][HTML] Oxidative stress and lipid mediators modulate immune cell functions in autoimmune diseases
P Wójcik, A Gęgotek, N Žarković… - International journal of …, 2021 - mdpi.com
Autoimmune diseases, including psoriasis, systemic lupus erythematosus (SLE), and
rheumatic arthritis (RA), are caused by a combination of environmental and genetic factors …
rheumatic arthritis (RA), are caused by a combination of environmental and genetic factors …
[HTML][HTML] Major phytocannabinoids and their related compounds: should we only search for drugs that act on cannabinoid receptors?
The most important discoveries in pharmacology, such as certain classes of analgesics or
chemotherapeutics, started from natural extracts which have been found to have effects in …
chemotherapeutics, started from natural extracts which have been found to have effects in …
Cannabis and cannabis edibles: a review
Cannabis is an excellent natural source of fiber and various bioactive cannabinoids. So far,
at least 120 cannabinoids have been identified, and more novel cannabinoids are gradually …
at least 120 cannabinoids have been identified, and more novel cannabinoids are gradually …
[HTML][HTML] Bioactive terpenes and their derivatives as potential SARS-CoV-2 proteases inhibitors from molecular modeling studies
LRL Diniz, Y Perez-Castillo, HA Elshabrawy… - Biomolecules, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel coronavirus; the
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Millions of cases and …
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Millions of cases and …
[HTML][HTML] Pharmacological properties, therapeutic potential and molecular mechanisms of JWH133, a CB2 receptor-selective agonist
The endocannabinoid system has attracted attention as a pharmacological target for several
pathological conditions. Cannabinoid (CB2)-selective agonists have been the focus of …
pathological conditions. Cannabinoid (CB2)-selective agonists have been the focus of …
[HTML][HTML] Pharmacological and toxicological effects of phytocannabinoids and recreational synthetic cannabinoids: Increasing risk of public health
Synthetic Cannabinoids (CBs) are a novel class of psychoactive substances that have
rapidly evolved around the world with the addition of diverse structural modifications to …
rapidly evolved around the world with the addition of diverse structural modifications to …
pysisyphus: Exploring potential energy surfaces in ground and excited states
J Steinmetzer, S Kupfer, S Gräfe - International Journal of …, 2021 - Wiley Online Library
Predicting the energetics of chemical transformations requires localizing stationary points on
a potential energy surface. While educts and products of a chemical reaction may be known …
a potential energy surface. While educts and products of a chemical reaction may be known …
[HTML][HTML] Neuroprotective effects of cannabidiol but not Δ9-tetrahydrocannabinol in rat hippocampal slices exposed to oxygen-glucose deprivation: studies with …
E Landucci, C Mazzantini, D Lana, PL Davolio… - International Journal of …, 2021 - mdpi.com
(1) Background: Over the past 10 years, a number of scientific studies have demonstrated
the therapeutic potential of cannabinoid compounds present in the Cannabis Sativa and …
the therapeutic potential of cannabinoid compounds present in the Cannabis Sativa and …