Role of neutrophils in the pathogenesis of nonalcoholic steatohepatitis

S Hwang, H Yun, S Moon, YE Cho… - Frontiers in endocrinology, 2021 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) includes a spectrum of liver disorders, from fatty
liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma …

[HTML][HTML] Microglia and BDNF at the crossroads of stressor related disorders: Towards a unique trophic phenotype

N Prowse, S Hayley - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Stressors ranging from psychogenic/social to neurogenic/injury to systemic/microbial can
impact microglial inflammatory processes, but less is known regarding their effects on …

Acute and sub-chronic effects of microplastics (3 and 10 µm) on the human intestinal cells HT-29

G Visalli, A Facciolà, M Pruiti Ciarello… - International journal of …, 2021 - mdpi.com
Due to ingestion of contaminated foods, the human gastrointestinal tract is the most likely
site of exposure to microplastics (MPs) with gut barrier dysfunction and intestinal …

Podocyte aging: why and how getting old matters

SJ Shankland, Y Wang, AS Shaw… - Journal of the …, 2021 - journals.lww.com
The effects of healthy aging on the kidney, and how these effects intersect with
superimposed diseases, are highly relevant in the context of the population's increasing …

Mesenchymal stromal cells for the treatment of ocular autoimmune diseases

JY Oh, RH Lee - Progress in retinal and eye research, 2021 - Elsevier
Mesenchymal stromal cells, commonly referred to as MSCs, have emerged as a promising
cell-based therapy for a range of autoimmune diseases thanks to several therapeutic …

Macrophage lineages in heart valve development and disease

AJ Kim, N Xu, KE Yutzey - Cardiovascular Research, 2021 - academic.oup.com
Heterogeneous macrophage lineages are present in the aortic and mitral valves of the heart
during development and disease. These populations include resident macrophages of …

The role of macrophages during zebrafish injury and tissue regeneration under infectious and non-infectious conditions

C Bohaud, MD Johansen, C Jorgensen… - Frontiers in …, 2021 - frontiersin.org
The future of regenerative medicine relies on our understanding of the mechanistic
processes that underlie tissue regeneration, highlighting the need for suitable animal …

Sterile injury repair and adhesion formation at serosal surfaces

SN Zwicky, D Stroka, J Zindel - Frontiers in immunology, 2021 - frontiersin.org
Most multicellular organisms have a major body cavity containing vital organs. This cavity is
lined by a mucosa-like serosal surface and filled with serous fluid which suspends many …

Sterile inflammation in thoracic transplantation

CC Frye, AI Bery, D Kreisel, HS Kulkarni - Cellular and Molecular Life …, 2021 - Springer
The life-saving benefits of organ transplantation can be thwarted by allograft dysfunction due
to both infectious and sterile inflammation post-surgery. Sterile inflammation can occur after …

[HTML][HTML] Hypoxia‐inducible factor‐dependent induction of myeloid‐derived netrin‐1 attenuates natural killer cell infiltration during endotoxin‐induced lung injury

NK Berg, J Li, B Kim, T Mills, G Pei, Z Zhao, X Li… - The FASEB …, 2021 - ncbi.nlm.nih.gov
Sepsis and sepsis‐associated lung inflammation significantly contribute to the morbidity and
mortality of critical illness. Here, we examined the hypothesis that neuronal guidance …