Arsenic-induced epigenetic changes in cancer development

WN Saintilnord, Y Fondufe-Mittendorf - Seminars in cancer biology, 2021 - Elsevier
Arsenic is a ubiquitous metalloid whose high levels of toxicity pose major health concerns to
millions of people worldwide by increasing susceptibility to various cancers and non-cancer …

First trimester mechanisms of gestational sac placental and foetal teratogenicity: a framework for birth cohort studies

JJ Adibi, AJ Layden, RL Birru, A Miragaia… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND The function of the gestational sac (GS) and the placenta in the closely
related processes of embryogenesis and teratogenicity in the first trimester has been …

Race/ethnicity-associated blood DNA methylation differences between Japanese and European American women: an exploratory study

MA Song, AE Seffernick, KJ Archer, KM Mori… - Clinical …, 2021 - Springer
Background Racial/ethnic disparities in health reflect a combination of genetic and
environmental causes, and DNA methylation may be an important mediator. We compared …

Prenatal stress in maternal hyperhomocysteinemia: impairments in the fetal nervous system development and placental function

AV Arutjunyan, GO Kerkeshko, YP Milyutina… - Biochemistry …, 2021 - Springer
The article presents current views on maternal hyperhomocysteinemia (HHcy) as an
important factor causing prenatal stress and impaired nervous system development in …

[HTML][HTML] The severity of SARS-CoV-2 infection is dictated by host factors? Epigenetic perspectives

DV Sethumadhavan, CA Jabeena… - Current Research in …, 2021 - Elsevier
The emergence of COVID-19, caused by SARS-CoV-2 poses a significant threat to humans
as it is highly contagious with increasing mortality. There exists a high degree of …

Folic acid supplementation does not decrease stillbirths and congenital malformations in a guide dog colony

KL Gonzales, TR Famula, LC Feng… - Journal of Small …, 2021 - Wiley Online Library
Objectives To investigate if maternal folic acid supplementation (5 mg) is associated with a
reduction of cleft palates, umbilical hernias, stillbirths and caesarean sections in a guide dog …

[HTML][HTML] The inorganic chemicals that surround us: role of tellurium, selenium and zinc on behavioural functions in mammals

EO Alvarez, OJ Sacchi, SG Ratti - Journal of Neurorestoratology, 2021 - Elsevier
Living organisms live in continuous interaction with its environment. During this process
changes in one can induce adaptive responses on the other. Many factors in the …

[HTML][HTML] A Brief Introduction to the Exposome and Human Health

MD Lucock - Exploratory Research and Hypothesis in …, 2021 - xiahepublishing.com
The exposome refers to all environmental exposures (internal and specific/general external)
that humans experience from conception through to death. This article examines the …

Пренатальный стресс при материнской гипергомоцистеинемии: нарушения развития нервной системы плода и функционального состояния плаценты

АВ Арутюнян, ГО Керкешко, ЮП Милютина… - Биохимия, 2021 - elibrary.ru
Обзор посвящён современным представлениям о гипергомоцистеинемии (ГГЦ) матери,
как важном факторе, вызывающем пренатальный стресс и нарушения развития …

Kdm6b confers Tfdp1 with the competence to activate p53 signalling in regulating palatogenesis

T Guo, X Han, J He, J Feng, J Jing, E Janečková, J Lei… - bioRxiv, 2021 - biorxiv.org
Epigenetic regulation plays extensive roles in diseases and development. Disruption of
epigenetic regulation not only increases the risk of cancer, but can also cause various …