Neuroinflammation, an inflammatory response within the central nervous system (CNS), is a
main hallmark of common neurodegenerative diseases, including Alzheimer's disease (AD) …

Glioblastoma is among the most aggressive forms of cancers, with a median survival of just
15–20 months for patients despite maximum clinical intervention. The majority of …

Mitochondria are signaling hubs responsible for the generation of energy through oxidative
phosphorylation, the production of key metabolites that serve the bioenergetic and …

Drug delivery to the brain is limited by poor penetration of pharmaceutical agents across the
blood-brain barrier (BBB), within the brain parenchyma, and into specific cells of interest …

Nanovesicles (NVs) are emerging as innovative, theranostic tools for cargo delivery.
Recently, surface engineering of NVs with membrane proteins from specific cell types has …

Switching microglia from a disease exacerbating,'pro-inflammatory'state into a
neuroprotective,'anti-inflammatory'phenotype is a promising strategy for addressing multiple …

Rett syndrome is a severe and progressive neurological disorder linked to mutations in the
MeCP2 gene. It has been suggested that immune alterations may play an active role in the …

Background Different approaches to reproduce cerebral palsy (CP) in animals, contribute to
the knowledge of the pathophysiological mechanism of this disease and provide a basis for …

Traumatic brain injury (TBI) is a major cause of mortality and morbidity in the pediatric
population. With advances in medical care, the mortality rate of pediatric TBI has declined …

Neurodegenerative diseases affect millions of people worldwide and the presence of
various physiological barriers limits the accessibility to the brain and reduces the efficacy of …