Inflammatory cytokine storms severity may be fueled by interactions of micronuclei and RNA viruses such as COVID-19 virus SARS-CoV-2. A hypothesis

M Kirsch-Volders, M Fenech - Mutation Research/Reviews in Mutation …, 2021 - Elsevier
In this review we bring together evidence that (i) RNA viruses are a cause of chromosomal
instability and micronuclei (MN),(ii) those individuals with high levels of lymphocyte MN have …

[HTML][HTML] MTHFR knockdown assists cell defense against folate depletion induced chromosome segregation and uracil misincorporation in DNA

MT Wu, WT Ye, YC Wang, PM Chen, JY Liu… - International journal of …, 2021 - mdpi.com
Folate depletion causes chromosomal instability by increasing DNA strand breakage, uracil
misincorporation, and defective repair. Folate mediated one-carbon metabolism has been …

[HTML][HTML] Diet as a potential moderator for genome stability and immune response in pediatric leukemia

S Wang, CA Maxwell, NM Akella - Cancers, 2021 - mdpi.com
Pediatric leukemias are the most prevalent cancers affecting children in developed
societies, with childhood acute lymphoblastic leukemia (ALL) being the most common …

Ruthenium complexes show promise when submitted to toxicological safety tests using alternative methodologies

TM Teixeira, IG Arraes, DC Abreu, KM Oliveira… - European Journal of …, 2021 - Elsevier
The number of cancer cases continues to increase worldwide, and unfortunately the main
systemic treatments available have numerous of side effects. Ruthenium complexes have …

[HTML][HTML] Use of micronucleus experiments for the detection of human cancer risks: a brief overview

A Nersesyan, M Mišík, A Cherkas… - Proceeding of the …, 2021 - mspsss.org.ua
Introduction. Micronuclei (MN) are small extranuclear DNA-containing structures that are
formed as a consequence of structural and numerical chromosomal aberrations. The …

[PDF][PDF] The importance of nutrition in gene expression, replication, repair and prevention of DNA damage

M Mohammadabadi… - Agricultural …, 2021 - academia.edu
The importance of nutrition in gene expression, replication, repair and prevention of DNA
damage Abstract Page 1 The importance of nutrition in gene expression, replication, repair and …

Micronuclei and Other Nuclear Anomalies in Exfoliated Buccal Mucosa Cells in Breast Cancer

NA Ismail - Iraq Medical Journal, 2021 - iraqmedj.org
Objectives: This study designed to assess the genomic instability between healthy women
and women with breast cancer by means of buccal cells micronucleus (MN) cytome assay …

[PDF][PDF] Diet as a Potential Moderator for Genome Stability and Immune Response in Pediatric Leukemia. Cancers 2021, 13, 413

S Wang, CA Maxwell, NM Akella - 2021 - open.library.ubc.ca
Pediatric leukemias are the most prevalent cancers affecting children in developed
societies, with childhood acute lymphoblastic leukemia (ALL) being the most common …

Etude cytogénétique des couples Marocains souffrant d'avortements spontanés précoces à répétition

H HOUMAID - 2021 - toubkal.imist.ma
L'avortement spontané est un problème courant au cours de la grossesse, il affecte presque
25 à 50% des femmes qui tentent à procréer. Il a été évalué qu'entre 30% à 60% de toutes …