Introduction: Obesity is a growing threat to public health, increasing risks of numerous
diseases and mortality, and impairing quality of life. If current trends continue, more than 1.1 …

Initially discovered as an impurity in insulin preparations, our understanding of the
hyperglycaemic hormone glucagon has evolved markedly over subsequent decades. With …

The gastrointestinal tract can assess the nutrient composition of ingested food. The nutrient-
sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the …

Obesity and Type 2 diabetes represent global health challenges, and there is an unmet
need for long-lasting and effective pharmacotherapies. Although long-acting glucagon-like …

We are currently facing an obesity pandemic, with worldwide obesity rates having tripled
since 1975. Obesity is one of the main risk factors for the development of non-communicable …

Obesity represents a major public health problem with a prevalence increasing at an
alarming rate worldwide. Continuous intensive efforts to elucidate the complex …

Both type 1 and type 2 diabetes mellitus are advancing at exponential rates, placing
significant burdens on health care networks worldwide. Although traditional pharmacologic …

Obesity is a global pandemic with a large health and economic burden worldwide.
Bodyweight is regulated by the ability of the CNS, and especially the hypothalamus, to …

Abstract Aim To compare a Mediterranean diet (MED) with a high‐fibre vegetarian diet
(HFV) in terms of hunger‐satiety perception through post‐prandial assessment of appetite …

Enteroendocrine cells (EECs) are specialized cells that are widely distributed throughout the
gastrointestinal tract. EECs sense luminal content and release hormones, such as: ghrelin …