Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
Pattern recognition receptors in health and diseases
D Li, M Wu - Signal transduction and targeted therapy, 2021 - nature.com
Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …
Senolytics and senomorphics: Natural and synthetic therapeutics in the treatment of aging and chronic diseases
SM Lagoumtzi, N Chondrogianni - Free Radical Biology and Medicine, 2021 - Elsevier
Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …
environmental factors, characterizing many types of somatic cells. It has been suggested as …
Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials
ATL Fiolet, TSJ Opstal, A Mosterd… - European Heart …, 2021 - academic.oup.com
Aims Recent randomized trials demonstrated a benefit of low-dose colchicine added to
guideline-based treatment in patients with recent myocardial infarction or chronic coronary …
guideline-based treatment in patients with recent myocardial infarction or chronic coronary …
Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19
A Gupta, MV Madhavan, TJ Poterucha… - Nature …, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state,
leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic …
leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic …
Relationship between systemic immune-inflammation index (SII) and the severity of stable coronary artery disease
M Candemir, E Kiziltunc, S Nurkoc… - Angiology, 2021 - journals.sagepub.com
Systemic immune-inflammation index (SII; platelet count× neutrophil-to-lymphocyte ratio), a
novel marker, predicts adverse clinical outcomes in coronary artery diseases (CAD). We …
novel marker, predicts adverse clinical outcomes in coronary artery diseases (CAD). We …
Lutein as a modulator of oxidative stress-mediated inflammatory diseases
YJ Ahn, H Kim - Antioxidants, 2021 - mdpi.com
Lutein is a xanthophyll carotenoid obtained from various foods, such as dark green leafy
vegetables and egg yolk. Lutein has antioxidant activity and scavenges reactive oxygen …
vegetables and egg yolk. Lutein has antioxidant activity and scavenges reactive oxygen …
Elevated markers of gut leakage and inflammasome activation in COVID‐19 patients with cardiac involvement
H Hoel, L Heggelund, DH Reikvam… - Journal of internal …, 2021 - Wiley Online Library
Background A high proportion of COVID‐19 patients have cardiac involvement, even those
without known cardiac disease. Downregulation of angiotensin converting enzyme 2 …
without known cardiac disease. Downregulation of angiotensin converting enzyme 2 …
Impact of COVID-19 on the cardiovascular system: a review of available reports
RS Soumya, TG Unni, KG Raghu - Cardiovascular drugs and therapy, 2021 - Springer
The recent emergence of the coronavirus disease 19 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) in China is now a global health …
respiratory syndrome coronavirus 2 (SARS-CoV-2) in China is now a global health …
Inflammation, oxidative stress, senescence in atherosclerosis: thioredoxine-1 as an emerging therapeutic target
K El Hadri, R Smith, E Duplus, C El Amri - International journal of …, 2021 - mdpi.com
Atherosclerosis is a leading cause of cardiovascular diseases (CVD) worldwide and
intimately linked to aging. This pathology is characterized by chronic inflammation, oxidative …
intimately linked to aging. This pathology is characterized by chronic inflammation, oxidative …