Osteoporosis is a common skeletal disease, affecting~ 200 million people around the world.
As a complex disease, osteoporosis is influenced by many factors, including diet (eg calcium …

Bone mass is a key determinant of osteoporosis and fragility fractures. Epidemiologic
studies have shown that a 10% increase in peak bone mass (PBM) at the population level …

Abstract βII spectrin, the most common isoform of non-erythrocyte spectrin, is a cytoskeleton
protein present in all nucleated cells. Interestingly, βII spectrin is essential for the …

Some osteoblasts embed within bone matrix, change shape, and become dendrite-bearing
osteocytes. The circuitry that drives dendrite formation during “osteocytogenesis” is poorly …

Osteoporosis is a metabolic bone disease with dysregulated coupling between bone
resorption and bone formation, which results in decreased bone mineral density. The …

Bone weight is critical to affect body conformation and stature in cattle. In this study, we
conducted a genome-wide association study for bone weight in Chinese Simmental beef …

MicroRNAs are emerging as critical post-transcriptional modulators in bone remodeling,
regulating the functions of osteoblasts and osteoclasts. Intercellular crosstalk between …

Background: The RANKL/RANK/OPG signaling pathway plays a critical role in
osteoclastogenesis and bone remodeling. The associations between sequence variants of …

Skeletal disorders, including fractures and osteoporosis, in laying hens cause major welfare
and economic problems. Although genetics have been shown to play a key role in bone …

Objective This paper will review how different methods employed to study bone loss in the
past were used to explore different questions and aspects of bone loss, how methodology …