Aerosol inhalation delivery of cefazolin in mice: Pharmacokinetic measurements and antibacterial effect

SV Valiulin, AA Onischuk, AM Baklanov… - International Journal of …, 2021 - Elsevier
Aerosol inhalation delivery of cefazolin, a broad-spectrum first-generation cephalosporin
antibiotic, was investigated. Inhalation system based on ultrasonic nebulizer was developed …

Why was there ever a warning not to use cephalosporins in the setting of a penicillin “allergy”?

E Macy - The Journal of Allergy and Clinical Immunology: In …, 2021 - Elsevier
It is now well-established that avoiding β-lactam antibiotics, when they are the drugs of
choice, results in significantly worse long-term global outcomes for patients. Much of this …

Empiric aztreonam is associated with increased mortality compared to beta-lactams in septic shock

RK Jaffa, J Hammer, LA Medaris, WE Anderson… - The American Journal of …, 2021 - Elsevier
Purpose To determine if aztreonam as initial empiric treatment of adult septic shock is
associated with increased mortality compared to the use of anti-pseudomonal beta-lactam …