Liver cancer most commonly develops in patients with chronic liver disease, the etiology of
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …

The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

The human sirtuins are a group of NAD+-dependent protein deacylases. They “erase” acyl
modifications from lysine residues in various cellular targets including histones, transcription …

Metabolic syndrome (MetS) is a chronic disease, including abdominal obesity, dyslipidemia,
hyperglycemia, and hypertension. It should be noted that the occurrence of MetS is closely …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver
diseases worldwide, including in Japan. The Japanese Society of Gastroenterology (JSGE) …

Background Malnutrition is seen in COVID-19 patients, and reducing malnutrition with
appropriate therapies may improve these patients' health. This case–control study aimed to …

Polyphenols are a group of micronutrients widely existing in plant foods including fruits,
vegetables, and teas that can improve nonalcoholic fatty liver disease (NAFLD). In this …

Purslane (Portulaca oleracea L.) is the richest green leafy vegetable source of omega‐3,
especially alpha linolenic acid (ALA). Experimental studies have shown beneficial effects of …

Fibrosis is defined by abnormal accumulation of extracellular matrix, which can affect
virtually every organ system under diseased conditions. Fibrotic tissue remodeling often …

Abstract Objective Randomized clinical trials (RCTs) examining the effects of resveratrol
supplementation on liver enzymes in non-alcoholic fatty liver disease (NAFLD) have …