Tuberculosis in the elderly

P Caraux-Paz, S Diamantis, B de Wazières… - Journal of Clinical …, 2021 - mdpi.com
The tuberculosis (TB) epidemic is most prevalent in the elderly, and there is a progressive
increase in the notification rate with age. Most cases of TB in the elderly are linked to the …

What is the optimum time to start antiretroviral therapy in people with HIV and tuberculosis coinfection? A systematic review and meta‐analysis

RM Burke, HM Rickman, V Singh… - Journal of the …, 2021 - Wiley Online Library
Background HIV and tuberculosis are frequently diagnosed concurrently. In March 2021,
World Health Organization recommended that antiretroviral therapy (ART) should be started …

Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms

AE Shapiro, JM Ross, M Yao, I Schiller… - Cochrane Database …, 2021 - cochranelibrary.com
Background Tuberculosis is a leading cause of infectious disease‐related death and is one
of the top 10 causes of death worldwide. The World Health Organization (WHO) …

Adjunct N-acetylcysteine treatment in hospitalized patients with HIV-associated tuberculosis dampens the oxidative stress in peripheral blood: Results from the …

IP Safe, EP Amaral, M Araujo-Pereira… - Frontiers in …, 2021 - frontiersin.org
Tuberculosis (TB) still causes significant morbidity and mortality worldwide, especially in
persons living with human immunodeficiency virus (HIV). This disease is hallmarked by …

Delayed diagnosis of tuberculosis in persons living with HIV in Eastern Europe: associated factors and effect on mortality—a multicentre prospective cohort study

C Kraef, A Bentzon, A Panteleev, A Skrahina… - BMC infectious …, 2021 - Springer
Background Early diagnosis of tuberculosis (TB) is important to reduce transmission,
morbidity and mortality in people living with HIV (PLWH). Methods PLWH with a diagnosis of …

[HTML][HTML] Tuberculosis among people living with HIV/AIDS in Jazan Region, Southwestern Saudi Arabia

MA Darraj, AA Abdulhaq, A Yassin, S Mubarki… - Journal of infection and …, 2021 - Elsevier
Background Tuberculosis (TB) and human immunodeficiency virus/acquired immune
deficiency syndrome (HIV/AIDS) infections are leading causes of morbidity and mortality …

Cost-effectiveness of a novel lipoarabinomannan test for tuberculosis in patients with human immunodeficiency virus

KP Reddy, CM Denkinger, T Broger… - Clinical Infectious …, 2021 - academic.oup.com
Background A novel urine lipoarabinomannan assay (FujiLAM) has higher sensitivity and
higher cost than the first-generation AlereLAM assay. We evaluated the cost-effectiveness of …

Diagnostic accuracy of Xpert MTB/RIF for tuberculous meningitis: systematic review and meta‐analysis

AV Hernandez, L de Laurentis, I Souza… - Tropical Medicine & …, 2021 - Wiley Online Library
Objective This systematic review evaluated the diagnostic accuracy of Xpert MTB/RIF to
detect tuberculous meningitis (TBM). Methods PubMed and five other databases were …

Health system determinants of tuberculosis mortality in South Africa: a causal loop model

M Osman, AS Karat, M Khan, SA Meehan… - BMC Health Services …, 2021 - Springer
Background Tuberculosis (TB) is a major public health concern in South Africa and TB-
related mortality remains unacceptably high. Numerous clinical studies have examined the …

[HTML][HTML] Tuberculosis in persons with sudden unexpected death, in Cape Town, South Africa

M Osman, J Verster, JJ Dempers, K Du Preez… - International Journal of …, 2021 - Elsevier
Background Globally, tuberculosis (TB) remains one of the leading causes of death from a
single infectious agent, but there has been little work to estimate mortality before the …