Bacterial respiratory tract infections are the hallmark of primary antibody deficiencies
(PADs). Because they are also among the most common infections in healthy individuals …

Inborn Errors of Immunity (IEI) comprise more than 450 inherited diseases, from which
selected patients manifest a frequent and early incidence of malignancies, mainly lymphoma …

Predominantly antibody deficiencies (PADs) encompass a heterogeneous group of
disorders characterized by low immunoglobulin serum levels in the presence or absence of …

Collective clinical and immunologic findings of defects in the CD27–CD70 axis indicate a
primary immunodeficiency associated with terminal B-cell development defect and immune …

Common variable immunodeficiency (CVID) is the most prevalent form of symptomatic
primary humoral immunodeficiencies characterized by failure in the final differentiation of B …

Abstract Background Intravenous immunoglobulins (IVIg) are the major treatment in inborn
errors of immunity (IEI) disorders; However, IVIg infusions show some adverse effects. We …

Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is a rare
primary immunodeficiency disorder characterized by recurrent infections and low …

Background HIGM syndrome is a rare form of primary immunodeficiencies characterized by
normal/increased amounts of serum IgM and decreased serum levels of other switched …

Although the majority of monogenic defects underlying primary immunodeficiency are
microlesions, large lesions like large deletions are rare and constitute less than 10% of …

Predominantly antibody deficiencies (PADs) are a heterogeneous group of primary
immunodeficiency disorders (PIDs), consisting of recurrent infections, autoimmunity …