Epigenetic regulation in fibrosis progress
T Xue, X Qiu, H Liu, C Gan, Z Tan, Y Xie, Y Wang… - Pharmacological …, 2021 - Elsevier
Fibrosis, a common process of chronic inflammatory diseases, is defined as a repair
response disorder when organs undergo continuous damage, ultimately leading to scar …
response disorder when organs undergo continuous damage, ultimately leading to scar …
Epigenetics-based therapeutics for myocardial fibrosis
X Li, Y Yang, S Chen, J Zhou, J Li, Y Cheng - Life sciences, 2021 - Elsevier
Myocardial fibrosis (MF) is a reactive remodeling process in response to myocardial injury. It
is mainly manifested by the proliferation of cardiac muscle fibroblasts and secreting …
is mainly manifested by the proliferation of cardiac muscle fibroblasts and secreting …
Antifibrotic effects and mechanisms of mesenchymal stem cell-derived exosomes in a systemic sclerosis mouse model: possible contribution of miR-196b-5p
H Baral, A Uchiyama, Y Yokoyama, A Sekiguchi… - Journal of …, 2021 - Elsevier
Abstract Background Systemic sclerosis (SSc) is a connective tissue disorder characterized
by the development of fibrosis in the skin and internal organs. Increasing evidence suggests …
by the development of fibrosis in the skin and internal organs. Increasing evidence suggests …
MicroRNA-130a is elevated in thyroid eye disease and increases lipid accumulation in fibroblasts through the suppression of AMPK
CL Hammond, E Roztocil, MO Gonzalez… - … & visual science, 2021 - iovs.arvojournals.org
Purpose: Thyroid eye disease (TED) is a condition that causes the tissue behind the eye to
become inflamed and can result in excessive fatty tissue accumulation in the orbit. Two …
become inflamed and can result in excessive fatty tissue accumulation in the orbit. Two …
SGLT2 promotes cardiac fibrosis following myocardial infarction and is regulated by miR‑141
G Li, C Zhao, S Fang - Experimental and Therapeutic …, 2021 - spandidos-publications.com
Cardiac fibrosis is a primary event during myocardial infarction (MI) progression, which
impairs cardiac function. The present study aimed to investigate the effect of SGLT2 on …
impairs cardiac function. The present study aimed to investigate the effect of SGLT2 on …
[HTML][HTML] MicroRNA-130a increases and predicts cardiotoxicity during adjuvant chemotherapy in human epidermal growth factor receptor-2-positive breast cancer
Q Feng, Y Ren, A Hou, J Guo, Z Mao, S Liu… - Journal of Breast …, 2021 - ncbi.nlm.nih.gov
Purpose This study aimed to investigate the changes in microRNA-130a (miR-130a) and its
correlation with cardiotoxicity during epirubicin/cyclophosphamide followed by docetaxel …
correlation with cardiotoxicity during epirubicin/cyclophosphamide followed by docetaxel …
A blood exosomal miRNA signature in acute respiratory distress syndrome
G Parzibut, M Henket, C Moermans… - Frontiers in Molecular …, 2021 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is a diffuse, acute, inflammatory lung disease
characterized by a severe respiratory failure. Recognizing and promptly treating ARDS is …
characterized by a severe respiratory failure. Recognizing and promptly treating ARDS is …
MicroRNAs in organ fibrosis: From molecular mechanisms to potential therapeutic targets
H Zhao, YL Feng, T Liu, JJ Wang, J Yu - Pathology-Research and Practice, 2021 - Elsevier
Fibrosis is caused by chronic tissue injury and characterized by the excessive deposition of
extracellular matrix (ECM) that ultimately results in organ failure and death. Owing to lacking …
extracellular matrix (ECM) that ultimately results in organ failure and death. Owing to lacking …
Expression profile of circulating MicroRNAs in dogs with cardiac hypertrophy: a pilot study
WB Ro, MH Kang, DW Song, SH Lee… - Frontiers in veterinary …, 2021 - frontiersin.org
This study aimed to identify the expression profile of circulating microRNAs in dogs with
eccentric or concentric cardiac hypertrophy. A total of 291 microRNAs in serum samples of …
eccentric or concentric cardiac hypertrophy. A total of 291 microRNAs in serum samples of …
Spermine-related DNA hypermethylation and elevated expression of genes for collagen formation are susceptible factors for chemotherapy-induced hand-foot …
Hand-foot syndrome (HFS) is a common capecitabine-based chemotherapy-related adverse
event (CRAE) in patients with colorectal cancer (CRC). It is of great significance to …
event (CRAE) in patients with colorectal cancer (CRC). It is of great significance to …