Ambient mass spectrometry imaging (AMSI) has attracted much attention in recent years. As
a kind of unlabeled molecular imaging technique, AMSI can enable in situ visualization of a …

Ambient ionization methods have become important tools in mass spectrometry. The LMJ-
SSP can significantly simplify/reduce lengthy sample preparation requirements associated …

Purpose To compare carbon‐13 (13C) MRSI of hyperpolarized [1‐13C] pyruvate
metabolism in a murine tumor model with mass spectrometric (MS) imaging of the …

Investigation on the distribution of persistent organic pollutants (POPs) in aquatic organisms
is of great importance for exploring the biological toxicity and health risks of environmental …

Suboptimal antibiotic dosing has been identified as one of the key drivers in the
development of multidrug‐resistant (MDR) bacteria that have become a global health …

Thermal desorption-electrospray ionization tandem mass spectrometry (TD-ESI/MS/MS) was
used to characterize the residual pesticides that were collectedfromthe surface of a …

Preceding decades have revealed a general decrease in the efficiency of pharmaceutical
research and development (R&D) as evidenced by a decline in productivity (measured in …

Ion mobility–mass spectrometry (IM-MS) is fundamentally a separation technique that can be
used in the same manner as solution-phase chromatography (LC), with numerous analytical …

Imaging mass spectrometry (IMS) typically requires extensive sample preparation involving
formalin fixation, staining, matrix deposition and embedding (eg optimum cutting …

This thesis explores further development of a liquid sampling technique called direct analyte
probednanoextraction (DAPNe) to analyse animal tissues and cells. DAPNe uses a …