Enhanced lung inflammatory response in whole-body compared to nose-only cigarette smoke-exposed mice

J Serré, AT Tanjeko, C Mathyssen… - Respiratory …, 2021 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterized by a
progressive and abnormal inflammatory response in the lungs, mainly caused by cigarette …

From Biomarkers to Novel Therapeutic Approaches in Chronic Obstructive Pulmonary Disease

HH Wang, SL Cheng - Biomedicines, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a heterogeneous and complex disorder.
In this review, we provided a comprehensive overview of biomarkers involved in COPD, and …

Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC‐Tg Mice

R Brown, DM Small, DF Doherty… - Mediators of …, 2021 - Wiley Online Library
Background. Elevated levels of the cysteine protease cathepsin S (CatS) are associated with
chronic mucoobstructive lung diseases such as cystic fibrosis (CF) and chronic obstructive …

GLIPR1 protects against cigarette smoke-induced airway inflammation via PLAU/EGFR signaling

W Peng, Y Wu, G Zhang, W Zhu, M Chang… - … Journal of Chronic …, 2021 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) is a major health problem
associated with high mortality worldwide. Cigarette smoke (CS) exposure is the main cause …

Drug Delivery in Respiratory Diseases: Current Opportunities, Molecular and Cellular Mechanism, and Future Challenges

DG Dastidar, D Ghosh, S Ghosh… - … Signalling Pathways in …, 2021 - Springer
Respiratory diseases are a major cause of concern throughout the world. Lung cancer,
chronic obstructive pulmonary disease (COPD), and asthma deserve special mention …

[图书][B] Chemical Tools to Interrogate and Inhibit Bacterial Exotoxins

MM Garland - 2021 - search.proquest.com
Antibiotic resistance is a significant emerging health threat. Exacerbating this problem is the
overprescription of antibiotics as well as a lack of development of new antibacterial agents …

IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases

G Del Val, E Schiffrin - US Patent 10,882,905, 2021 - Google Patents
2020-09-03 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
com/? family= 55453181&utm_source= google_patent&utm_medium …