A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone
formation and resorption, pathological conditions affecting the bone may arise. In recent …

The TP53 gene is arguably the most important tumor suppressor gene known, contributing
multifaceted roles to the process of tumor development. Its protein product p53, is a crucial …

Background An increasing number of studies have shown that lncRNAs are crucial for the
control of hormones and the regulation of various physiological processes in the human …

The spatial partitioning of the transcriptome in the cell is an important form of gene-
expression regulation. Here, we address how intron retention influences the spatio-temporal …

Long non-coding RNAs (lncRNAs) can play significant regulatory roles in cells that affect the
development and acquired drug resistance of lung cancer. Herein, we report that lncRNA …

Gastrointestinal (GI) cancers, including colorectal, gastric, hepatic, esophageal, and
pancreatic tumors, are responsible for large numbers of deaths around the world …

The human transcriptome contains many non-coding RNAs (ncRNAs), which play important
roles in gene regulation. Long noncoding RNAs (lncRNAs) are an important class of …

Long non-coding RNAs (lncRNAs) are a group of non-protein coding RNAs with a length of
more than 200 bp. The lncRNA taurine up-regulated gene 1 (TUG1) is abnormally …

Non-coding natural antisense transcripts (ncNATs) are regulatory RNA sequences that are
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …

In mammals, a large part of the gene expression products come from the non-coding
ribonucleotide sequences of the protein. These short and long sequences are within the …