Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Hemorrhagic transformation (HT) is a common complication in patients with acute ischemic
stroke. It occurs when peripheral blood extravasates across a disrupted blood brain barrier …

Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients
with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide …

The optimal blood pressure (BP) management in acute ischaemic stroke (AIS) and acute
intracerebral haemorrhage (ICH) remains controversial. These European Stroke …

Background High systolic blood pressure after successful endovascular therapy for acute
ischaemic stroke is associated with increased risk of intraparenchymal haemorrhage …

Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

Stroke is a major contributor to death and disability worldwide. Prior to modern therapy, post-
stroke mortality was approximately 10% in the acute period, with nearly one-half of the …

Importance The underenrollment of women in randomized clinical trials represents a threat
to the validity of the evidence supporting clinical guidelines and potential disparities in …

Ischemic stroke is a leading cause of death worldwide; currently available treatment
approaches for ischemic stroke are to restore blood flow, which reduce disability but are time …

Acute ischemic strokes (AIS) and hemorrhagic strokes lead to disabling neuropsychiatric
and cognitive deficits. A serious and fatal complication of AIS is the occurrence of …