Neurons are highly polarized cells with a single axon and multiple dendrites derived from
the cell body to form tightly associated pre-and postsynaptic compartments. As the …

The endogenous cannabinoid transmitter system regulates synaptic transmission
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …

Recent evidence suggests that nano-organization of proteins within synapses may control
the strength of communication between neurons in the brain. The unique subsynaptic …

This review summarizes our current knowledge of human disease-relevant genetic variants
within the family of voltage gated Ca2+ channels. Ca2+ channelopathies cover a wide …

Voltage-gated calcium channels are the principal conduits for depolarization-mediated
Ca2+ entry into excitable cells. In this review, the biophysical properties of the relevant …

Light-evoked voltage responses of rod and cone photoreceptor cells in the vertebrate retina
must be converted to a train of synaptic vesicle release events for transmission to …

Rod photoreceptors (PRs) use ribbon synapses to transmit visual information. To signal 'no
light detected'they release glutamate continually to activate post-synaptic receptors. When …

Establishing a reliable electrophysiological recording platform is crucial for cardiology and
neuroscience research. Noninvasive and label-free planar multitransistors and …

Rab-interacting molecule (RIM)-binding protein 2 (BP2) is a multidomain protein of the
presynaptic active zone (AZ). By binding to RIM, bassoon (Bsn), and voltage-gated Ca 2+ …

Neurodevelopmental disorders (NDDs) that affect cognition, social interaction, and learning,
including autism spectrum disorder (ASD) and intellectual disability (ID), have a strong …