Acute traumatic spinal cord injury

I Eli, DP Lerner, Z Ghogawala - Neurologic clinics, 2021 - neurologic.theclinics.com
Acute traumatic spinal cord injury (SCI) is typically associated with devastating outcomes.
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …

[HTML][HTML] Acute spinal cord injury: Pathophysiology and pharmacological intervention

Y Zhang, A Al Mamun, Y Yuan… - Molecular …, 2021 - spandidos-publications.com
Spinal cord injury (SCI) is one of the most debilitating of all the traumatic conditions that
afflict individuals. For a number of years, extensive studies have been conducted to clarify …

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

[HTML][HTML] Management of acute traumatic spinal cord injury: a review of the literature

TY Wang, C Park, H Zhang, S Rahimpour… - Frontiers in …, 2021 - frontiersin.org
Traumatic spinal cord injury (TSCI) is a debilitating disease that poses significant functional
and economic burden on both the individual and societal levels. Prognosis is dependent on …

Neuroimmunological therapies for treating spinal cord injury: Evidence and future perspectives

JCT Chio, KJ Xu, P Popovich, S David… - Experimental …, 2021 - Elsevier
Spinal cord injury (SCI) has a complex pathophysiology. Following the initial physical
trauma to the spinal cord, which may cause vascular disruption, hemorrhage, mechanical …

A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury

N Hejrati, MG Fehlings - Current Opinion in Pharmacology, 2021 - Elsevier
Traumatic spinal cord injuries (SCIs) have far-reaching physical, social, and financial
consequences. While medical advancements have improved supportive therapeutic …

[HTML][HTML] Physical and biological engineering of polymer scaffolds to potentiate repair of spinal cord injury

Y Luo, F Xue, K Liu, B Li, C Fu, J Ding - Materials & Design, 2021 - Elsevier
Although the mortality rates of patients suffering from spinal cord injury (SCI) have
decreased as the modalities of clinical therapy have been improved, the recovery of motor …

Updated review: the steroid controversy for management of spinal cord injury

JA Canseco, BA Karamian, DR Bowles… - World neurosurgery, 2021 - Elsevier
Background Acute spinal cord injury (ASCI) is a devastating event that can have a profound
impact on the lives of patients and their families. While no definitive medical treatment exists …

[HTML][HTML] Clinical guidelines for neurorestorative therapies in spinal cord injury (2021 China version)

X Guo, Y Feng, T Sun, S Feng, J Tang, L Chen… - Journal of …, 2021 - Elsevier
Treatment of spinal cord injury (SCI) remains challenging. Considering the rapid
developments in neurorestorative therapies for SCI, we have revised and updated the …

[HTML][HTML] Delayed administration of high dose human immunoglobulin G enhances recovery after traumatic cervical spinal cord injury by modulation of …

JCT Chio, J Wang, V Surendran, L Li… - Neurobiology of …, 2021 - Elsevier
Background/introduction The neuroinflammatory response plays a major role in the
secondary injury cascade after traumatic spinal cord injury (SCI). To date, systemic anti …