Cellular responses to the efferocytosis of apoptotic cells

C Yin, B Heit - Frontiers in Immunology, 2021 - frontiersin.org
The rapid and efficient phagocytic clearance of apoptotic cells, termed efferocytosis, is a
critical mechanism in the maintenance of tissue homeostasis. Removal of apoptotic cells …

SNX10‐mediated LPS sensing causes intestinal barrier dysfunction via a caspase‐5‐dependent signaling cascade

X Wang, J Ni, Y You, G Feng, S Zhang, W Bao… - The EMBO …, 2021 - embopress.org
Altered intestinal microbial composition promotes intestinal barrier dysfunction and triggers
the initiation and recurrence of inflammatory bowel disease (IBD). Current treatments for IBD …

The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7

E Trofimenko, Y Homma, M Fukuda, C Widmann - Cell reports, 2021 - cell.com
Endocytosis and endosome dynamics are controlled by proteins of the small GTPase Rab
family. Besides possible recycling routes to the plasma membrane and various organelles …

Membrane-binding mechanism of the EEA1 FYVE domain revealed by multi-scale molecular dynamics simulations

AH Larsen, L Tata, LH John… - PLOS Computational …, 2021 - journals.plos.org
Early Endosomal Antigen 1 (EEA1) is a key protein in endosomal trafficking and is
implicated in both autoimmune and neurological diseases. The C-terminal FYVE domain of …

Functional characterization of the Rab11A-dependent secretory pathway in Toxoplasma gondii

S Chehade - 2021 - theses.hal.science
Toxoplasma gondii possesses an armada of secreted virulent factors that enable parasite
invasion and survival into the host cell. These factors are contained in specific secretory …

[图书][B] Uptake of a Fluorescently Labeled Alkamide by Mammalian Cells

SE Johnstone - 2021 - search.proquest.com
Alkamides are fatty acid amides produced by a variety of different plants. Alkamides exert
immunomodulatory and anti-nociceptive effects and most studies of their mechanism of …

[PDF][PDF] Endosomal Trafficking is disrupted in Neurodevelopmental Disorders

SC Romero, R Dzvurumi, A Crockett, A Lombardo… - 2021 - academia.edu
Endosomal trafficking has been implicated in several neurodevelopmental disorders
including Rett Syndrome (RTT) and Schizophrenia (SZ). Endosomal proteins have been …