Neonatal red blood cell transfusion

A Villeneuve, V Arsenault, J Lacroix, M Tucci - Vox sanguinis, 2021 - Wiley Online Library
Transfusions are more common in premature infants with approximately 40% of low birth
weight infants and up to 90% of extremely low birth weight infants requiring red blood cell …

[HTML][HTML] Anemia and red blood cell transfusions, cerebral oxygenation, brain injury and development, and neurodevelopmental outcome in preterm infants: a …

WS Kalteren, EA Verhagen, JP Mintzer, AF Bos… - Frontiers in …, 2021 - frontiersin.org
Background: Anemia remains a common comorbidity of preterm infants in the neonatal
intensive care unit (NICU). Left untreated, severe anemia may adversely affect organ …

Variation in neonatal transfusion practice

RM Patel, JE Hendrickson, ME Nellis, R Birch… - The Journal of …, 2021 - Elsevier
Objective To estimate the incidence of blood product transfusion, including red blood cells,
platelets, and plasma, and characterize pretransfusion hematologic values for infants during …

Association of blood donor sex and age with outcomes in very low-birth-weight infants receiving blood transfusion

RM Patel, J Lukemire, N Shenvi, C Arthur… - JAMA Network …, 2021 - jamanetwork.com
Importance There are conflicting data on the association between blood donor
characteristics and outcomes among patients receiving transfusions. Objective To evaluate …

Anemia of prematurity: how low is too low?

CC Cibulskis, A Maheshwari, R Rao… - Journal of …, 2021 - nature.com
Anemia of prematurity (AOP) is a common condition with a well-described chronology, nadir
hemoglobin levels, and timeline of recovery. However, the underlying pathophysiology and …

[HTML][HTML] Iron and neurodevelopment in preterm infants: a narrative review

KR German, SE Juul - Nutrients, 2021 - mdpi.com
Iron is critical for brain development, playing key roles in synaptogenesis, myelination,
energy metabolism and neurotransmitter production. NICU infants are at particular risk for …

[HTML][HTML] Transfusions and neurodevelopmental outcomes in extremely low gestation neonates enrolled in the PENUT Trial: a randomized clinical trial

PT Vu, RK Ohls, DE Mayock, KR German… - Pediatric …, 2021 - nature.com
Background Outcomes of extremely low gestational age neonates (ELGANs) may be
adversely impacted by packed red blood cell (pRBC) transfusions. We investigated the …

[HTML][HTML] Restrictive versus liberal transfusion thresholds in very low birth weight infants: A systematic review with meta-analysis

P Wang, X Wang, H Deng, L Li, W Chong, Y Hai… - PLoS …, 2021 - journals.plos.org
Background To assess the efficacy and safety of restrictive versus liberal red blood cell
transfusion thresholds in very low birth weight infants. Methods We searched MEDLINE …

Transfusion in neonatal patients: review of evidence-based guidelines

PE Zerra, CD Josephson - Clinics in laboratory medicine, 2021 - labmed.theclinics.com
Although a critical therapy in the management of hospitalized pediatric patients, 1, 2
transfusion of red blood cells (RBCs), platelets, and fresh frozen plasma (FFP) in neonatal …

Enteral iron supplementation in infants born extremely preterm and its positive correlation with neurodevelopment; post hoc analysis of the preterm erythropoietin …

KR German, PT Vu, BA Comstock, RK Ohls… - The Journal of …, 2021 - Elsevier
Objectives To test whether an increased iron dose is associated with improved
neurodevelopment as assessed by the Bayley Scales of Infant Development, third edition …