Strategies to improve antimicrobial utilization with a special focus on developing countries

B Godman, A Egwuenu, M Haque, OO Malande… - Life, 2021 - mdpi.com
Antimicrobial resistance (AMR) is a high priority across countries as it increases morbidity,
mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally …

Optimising antimicrobial use in humans–review of current evidence and an interdisciplinary consensus on key priorities for research

E Charani, M McKee, R Ahmad… - The Lancet Regional …, 2021 - thelancet.com
Addressing the silent pandemic of antimicrobial resistance (AMR) is a focus of the 2021 G7
meeting. A major driver of AMR and poor clinical outcomes is suboptimal antimicrobial use …

Assessment of WHO antibiotic consumption and access targets in 76 countries, 2000–15: an analysis of pharmaceutical sales data

EY Klein, M Milkowska-Shibata, KK Tseng… - The Lancet Infectious …, 2021 - thelancet.com
Summary Background The WHO Access, Watch, and Reserve (AWaRe) antibiotic
classification framework aims to balance appropriate access to antibiotics and stewardship …

Hospital antibiotic prescribing patterns in adult patients according to the WHO Access, Watch and Reserve classification (AWaRe): Results from a worldwide point …

I Pauwels, A Versporten, N Drapier… - Journal of …, 2021 - academic.oup.com
Abstract Objectives The WHO Access, Watch and Reserve (AWaRe) classification has been
developed to support countries and hospitals in promoting rational use of antibiotics while …

Antibiotic prescribing patterns in Ghana, Uganda, Zambia and Tanzania hospitals: results from the global point prevalence survey (G-PPS) on antimicrobial use and …

N D'Arcy, D Ashiru-Oredope, O Olaoye, D Afriyie… - Antibiotics, 2021 - mdpi.com
Antimicrobial resistance (AMR) remains an important global public health issue with
antimicrobial misuse and overuse being one of the main drivers. The Global Point …

A global point prevalence survey of antimicrobial use in neonatal intensive care units: the no-more-antibiotics and resistance (NO-MAS-R) study

P Prusakov, DA Goff, PS Wozniak, A Cassim… - …, 2021 - thelancet.com
Background Global assessment of antimicrobial agents prescribed to infants in the neonatal
intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods We …

Pseudomonas aeruginosa: a clinical and genomics update

AC Pelegrin, M Palmieri, C Mirande… - FEMS Microbiology …, 2021 - academic.oup.com
Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …

Neonatal Sepsis: The Impact of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae

S Mukherjee, S Mitra, S Dutta, S Basu - Frontiers in Medicine, 2021 - frontiersin.org
The convergence of a vulnerable population and a notorious pathogen is devastating, as
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …

Variations in the consumption of antimicrobial medicines in the European Region, 2014–2018: findings and implications from ESAC-Net and WHO Europe

J Robertson, V Vlahović-Palčevski, K Iwamoto… - Frontiers in …, 2021 - frontiersin.org
Background: Surveillance of antimicrobial consumption (AMC) is important to address
inappropriate use. AMC data for countries in the European Union (EU) and European …

Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an …

KM Thomson, C Dyer, F Liu, K Sands… - The Lancet Infectious …, 2021 - thelancet.com
Background Sepsis is a major contributor to neonatal mortality, particularly in low-income
and middle-income countries (LMICs). WHO advocates ampicillin–gentamicin as first-line …