Cross-resistance to abiraterone and enzalutamide in castration resistance prostate cancer cellular models is mediated by AR transcriptional reactivation
I Simon, S Perales, L Casado-Medina… - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer is the second most common cancer in males. In prostate
cancer cells, androgens bind and activate the intracellular mediator called Androgen …
cancer cells, androgens bind and activate the intracellular mediator called Androgen …
In silico docking of phytocompounds to identify potent inhibitors of signaling pathways involved in prostate cancer
B Jonnalagadda, S Arockiasamy… - Journal of Biomolecular …, 2021 - Taylor & Francis
Androgens and androgen receptors (AR) are the master regulators in the development of
prostate cancer. Majority of the patients show positive response to surgical or medical …
prostate cancer. Majority of the patients show positive response to surgical or medical …
A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study
NA Abdul-Rida, AM Farhan, NA Al-Masoudi… - Molecular …, 2021 - Springer
New pregnene analogs of N-hydroxamic acid 6, imino-propane hydrazides 7 and 8 as well
as the aryl amides 9–11, oxadiazole, pyrazole and sulfinyl analogs 13–15, via the hydrazide …
as the aryl amides 9–11, oxadiazole, pyrazole and sulfinyl analogs 13–15, via the hydrazide …
L'overespressione di ERG promuove l'attivazione del signalling IFN, la deregolazione delle KRT e influenza la composizione del secretoma in un modello in vitro di …
MG DE MARINO - 2021 - irinsubria.uninsubria.it
The high incidence of TMPRSS2: ERG fusion gene and ERG subsequent overexpression is
still poorly characterized from a clinicopathologic point of view. This project aimed to …
still poorly characterized from a clinicopathologic point of view. This project aimed to …
Somatic copy number alterations reveal insight in drivers of resistance as a response to specific treatments
N Nijs - 2021 - studenttheses.uu.nl
When you have cancer, you get treated with a drug, but this treatment is not always fully
effective. There is a chance that you get resistant against this drug, with other words the drug …
effective. There is a chance that you get resistant against this drug, with other words the drug …