The discovery of leptin was intrinsically associated with its ability to regulate body weight.
However, the effects of leptin are more far-reaching and include profound glucose-lowering …

Leptin has emerged over the past 2 decades as a key hormone secreted by adipose tissue
that conveys information on energy stores. Leptin is considered an important regulator of …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

Leptin is a principal adipose-derived hormone mostly implicated in the regulation of energy
balance through the activation of anorexigenic neuronal pathways. Comprehensive studies …

The adipocyte-derived 'satiety promoting'hormone, leptin, has been identified as a key
central regulator of body weight and fertility, such that its absence leads to obesity and …

Obesity is a pandemic condition of complex etiology, resulting from the increasing exposition
to obesogenic environmental factors combined with genetic susceptibility. In the past two …

Pharmacotherapy in pediatric obesity: current evidence and l... : Current Opinion in
Endocrinology, Diabetes and Obesity Pharmacotherapy in pediatric obesity: current evidence …

With the improvement of living conditions and the popularity of unhealthy eating and living
habits, obesity is becoming a global epidemic. Obesity is now recognized as a disease that …

Leptin is a hormone which functions in the regulation of energy homeostasis via
suppression of appetite. In zebrafish, there are two paralogous genes encoding leptin …

Purpose Obesity is a major public health problem. Understanding which genes contribute to
obesity may better predict individual risk and allow development of new therapies. Because …