Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …

Abstract Interleukin-33 (IL-33), a member of the IL-1 family, and its cognate receptor,
Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma …

The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …

Our daily rhythmicity is controlled by a circadian clock with a specific set of genes located in
the suprachiasmatic nucleus in the hypothalamus. Mast cells (MCs) are major effector cells …

Coronary artery disease (CAD) is a pandemic disease that is highly preventable as shown
by secondary prevention. Primary prevention is preferred knowing that 50% of the …

Lipoproteins interact with immune cells, macrophages and endothelial cells-key players of
the innate and adaptive immune system. High-density lipoprotein (HDL) particles seem to …

Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine highly expressed by epithelial
cells and several innate and adaptive immune cells. TSLP exerts its biological effects by …

Dysregulated fatty acid metabolism is clinically associated with eosinophilic allergic
diseases, including severe asthma and chronic rhinosinusitis. This study aimed to …