[HTML][HTML] Thiazole, triazole, thio-and semicarbazone derivatives-Promising moieties for drug development for the treatment of tuberculosis
Thiazole, triazole, thio and semicarbazones are privileged motifs that act as
pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB) …
pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB) …
Development of a multi-target anticancer Sn (ii) pyridine-2-carboxaldehyde thiosemicarbazone complex
J Wu, T Yang, X Wang, W Li, M Pang, H Sun… - Dalton …, 2021 - pubs.rsc.org
In this study, we proposed to design effective multi-target anticancer agents based on the
chelation of nontoxic metals with ligands that possess anticancer activity. In total, five Sn (II) …
chelation of nontoxic metals with ligands that possess anticancer activity. In total, five Sn (II) …
The synthesis of novel piperazine-benzodioxole substituted phthalocyanines and investigation of their α-amylase and tyrosinase inhibition properties
İ Değirmencioğlu, FO Tuncay, U Cakmak… - Journal of …, 2021 - Elsevier
Abstract In this study, novel 1-(benzo [d][1, 3] dioxol-5-ylmethyl) piperazine substituted
phthalocyanine Zn (II), Pb (II) and Co (II) complexes (ZnPc, PbPc, CoPc) were synthesized …
phthalocyanine Zn (II), Pb (II) and Co (II) complexes (ZnPc, PbPc, CoPc) were synthesized …
Therapeutic potential of N4-substituted thiosemicarbazones as new urease inhibitors: Biochemical and in silico approach
Urease enzyme plays a key role in pathogenesis of gastritis and peptic ulcers. Its inhibition
averts our bodies from many disorders including formation of urinary calculi. In agriculture …
averts our bodies from many disorders including formation of urinary calculi. In agriculture …
A new series of benzoxazole‐based SIRT1 modulators for targeted therapy of non‐small‐cell lung cancer
In an attempt to identify potential anticancer agents for non‐small‐cell lung cancer (NSCLC)
targeting sirtuin 1 (SIRT1), the synthesis of a new series of benzoxazoles (3a–i) was carried …
targeting sirtuin 1 (SIRT1), the synthesis of a new series of benzoxazoles (3a–i) was carried …
Design, synthesis and antiviral evaluation of new N-(4)-(benzo [d][1, 3]-dioxol-5-yl) thiosemicarbazone derivatives
SY Abbas, WM Tohamy, WM Basyouni… - Egyptian Journal of …, 2021 - journals.ekb.eg
A new series of N-(4)-substituted thiosemicarbazone derivatives 4-8 incorporating a benzo
[d][1, 3] dioxole moiety were synthesized through the reaction of N-(4)-(benzo [d][1, 3] dioxol …
[d][1, 3] dioxole moiety were synthesized through the reaction of N-(4)-(benzo [d][1, 3] dioxol …
In vitro cytotoxic evaluation and apoptotic effects of dillapiole on human nasal squamous cell carcinoma
Dillapiole is one of the major compounds in Peperomia pellucida. Dillapiole exerts
cytotoxicity effect on several cancer cells such as breast and colon with a minimal effect on …
cytotoxicity effect on several cancer cells such as breast and colon with a minimal effect on …
[PDF][PDF] An one-Spot Synthesis of 1, 3, 4-Thiadiazole Derivative by Conventional and Modern Technique
B Dhotre, A Bharade, R Khalapure, J Jagtap, S Sampal - 2021 - lbscpartur.co.in
An efficient and one-pot synthesis is described for the 1, 3, 4-thiadiazole derivatives by a
conventional and modern technologies such as microwave irradiation. The reaction of …
conventional and modern technologies such as microwave irradiation. The reaction of …