The chemistry and biology of guanidine secondary metabolites

RGS Berlinck, DI Bernardi, T Fill… - Natural Product …, 2021 - pubs.rsc.org
Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

[HTML][HTML] Physalin pool from Physalis angulata L. leaves and physalin D inhibit P2X7 receptor function in vitro and acute lung injury in vivo

JCC Arruda, NC Rocha, EG Santos… - Biomedicine & …, 2021 - Elsevier
P2X7 receptor promotes inflammatory response and neuropathic pain. New drugs capable
of impairing inflammation and pain-reducing adverse effects extracted from plant extracts …

Model-free approach for the configurational analysis of marine natural products

M Köck, M Reggelin, S Immel - Marine Drugs, 2021 - mdpi.com
The NMR-based configurational analysis of complex marine natural products is still not a
routine task. Different NMR parameters are used for the assignment of the relative …

[HTML][HTML] Pyrrolactams from marine sponge Stylissa massa collected from Myanmar and their anti-vpr activities

NN Win, T Kodama, AA Aye, KZW Lae… - Chemical and …, 2021 - jstage.jst.go.jp
A new brominated pyrrolactam stylissaol A (1) together with four known analogues, 2-
bromoaldisine, aldisine, spongiacidin D, and Z-hymenialdisine, were isolated from the …

Efficient construction of the hexacyclic ring core of palau'amine: the p K a concept for proceeding with unfavorable equilibrium reactions

E Ohashi, S Karanjit, A Nakayama, K Takeuchi… - Chemical …, 2021 - pubs.rsc.org
Palau'amine has received a great deal of attention as an attractive synthetic target due to its
intriguing molecular architecture and significant immunosuppressive activity, and we …