Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Nanocarrier-based drug delivery systems hold impressive promise for biomedical
application because of their excellent water dispersibility, prolonged blood circulation time …

This article provides a broad spectrum about the nanoprodrug fabrication advances co‐
driven by prodrug and nanotechnology development to potentiate cancer treatment. The …

Carrier-free prodrug-nanoassemblies have emerged as promising nanomedicines. In
particular, the self-assembled nanoparticles (NPs) composed of homodimeric prodrugs with …

Nanomedicines generally consisting of carrier materials with small fractions of active
pharmaceutical ingredients (API) have long been used to improve the pharmacokinetics and …

The precise accumulation and extended retention of nanomedicines in the tumor tissue has
been highly desired for cancer therapy. Here a novel supramolecular‐peptide derived …

Drug delivery with nanoparticles is sometimes compared to an attack with a Trojan Horse.
The drugs are hidden in nanoparticles and enter the unsuspecting cells in a stealth‐like …

We describe here a method to synthesize ultrasmall nanocapsules with a diameter of 6 nm,
exhibiting a well‐defined core–shell morphology. Remarkably, the nanocapules are …

We report that the self‐assembly of drug amphiphiles, Evans blue conjugated camptothecin
prodrug (EB‐CPT), can be modulated by another anticancer drug paclitaxel (PTX), resulting …