Shared and distinct mechanisms of skeletal muscle atrophy: a narrative review

D Wilburn, A Ismaeel, S Machek, E Fletcher… - Ageing research …, 2021 - Elsevier
Maintenance of skeletal muscle mass and function is an incredibly nuanced balance of
anabolism and catabolism that can become distorted within different pathological conditions …

Old and new biomarkers for volumetric muscle loss

K Downing, R Prisby, V Varanasi, J Zhou, Z Pan… - Current opinion in …, 2021 - Elsevier
Volumetric muscle loss (VML) impacts skeletal muscles and causes damage to associated
tissues such as blood vessels and other structural tissues. Despite progress in the VML field …

SR Ca2+ handling in unbranched, immediately post-necrotic fast-twitch mdx fibres is similar to wt littermates

S Chan, SLL Kueh, JW Morley, SI Head - bioRxiv, 2021 - biorxiv.org
There is a lack of consensus in the literature regarding the effects of dystrophin deficiency on
the Ca2+-handling properties of the SR in mdx mice, an animal model of Duchenne …

[PDF][PDF] Implication de la voie RANK/RANKL/OPG dans la physiopathologie musculaire et potentiel thérapeutique de l'anti-RANKL pour la dystrophie musculaire de …

D Hamoudi - 2021 - core.ac.uk
Duchenne muscular dystrophy (DMD) is a genetic neuromuscular disorder caused by
mutations in the gene encoding dystrophin located on chromosome Xp21. The absence of …

MRTF-A regulates Ca2+ release through CACNA1S

C Liang, Y Xu, Z Peng, Y Luo, T Zhang - Journal of Biosciences, 2021 - Springer
Gene therapy is considered a potential treatment for Duchenne muscular dystrophy (DMD).
Researchers have been working on this for many years to find effective therapeutic targets …

Disruption of the microphysiological niche alters matrix deposition and causes loss of mitochondrial Ca2+ control in skeletal muscle fibers

C Gineste, S Youhanna, SU Vorrink, S Henriksson… - bioRxiv, 2021 - biorxiv.org
Cells rapidly lose their physiological phenotype upon disruption of their extracellular matrix
(ECM)-intracellular cytoskeleton interactions. Here, we investigated acute effects of ECM …