[HTML][HTML] The complex interactions between rotavirus and the gut microbiota

AHJ Kim, MP Hogarty, VC Harris… - Frontiers in cellular and …, 2021 - frontiersin.org
Human rotavirus (HRV) is the leading worldwide cause of acute diarrhea-related death in
children under the age of five. RV infects the small intestine, an important site of colonization …

Lactiplantibacillus plantarum as a Potential Adjuvant and Delivery System for the Development of SARS-CoV-2 Oral Vaccines

J Villena, C Li, MG Vizoso-Pinto, J Sacur, L Ren… - Microorganisms, 2021 - mdpi.com
The most important characteristics regarding the mucosal infection and immune responses
against the Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) as well as the current …

Emerging roles of gut virome in pediatric diseases

V Fulci, L Stronati, S Cucchiara, I Laudadio… - International journal of …, 2021 - mdpi.com
In the last decade, the widespread application of shotgun metagenomics provided extensive
characterization of the bacterial “dark matter” of the gut microbiome, propelling the …

Update on rotavirus vaccine underperformance in low-to middle-income countries and next-generation vaccines

B Lee - Human Vaccines & Immunotherapeutics, 2021 - Taylor & Francis
In the decade since oral rotavirus vaccines (ORV) were recommended by the World Health
Organization for universal inclusion in all national immunization programs, significant yet …

Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures

H Ingle, E Hassan, J Gawron, B Mihi, Y Li… - Mucosal …, 2021 - nature.com
Although they globally cause viral gastroenteritis in children, astroviruses are understudied
due to the lack of well-defined animal models. While murine astroviruses (muAstVs) …

The 5-HT3 Receptor Affects Rotavirus-Induced Motility

M Hagbom, A Hellysaz, C Istrate, J Nordgren… - Journal of …, 2021 - Am Soc Microbiol
Rotavirus infection is highly prevalent in children, and the most severe effects are diarrhea
and vomiting. It is well accepted that the enteric nervous system (ENS) is activated and plays …

Identification of a ruminant origin group B rotavirus associated with diarrhea outbreaks in foals

T Uprety, CC Sreenivasan, BM Hause, G Li… - Viruses, 2021 - mdpi.com
Equine rotavirus group A (ERVA) is one of the most common causes of foal diarrhea.
Starting in February 2021, there was an increase in the frequency of severe watery to …

Understanding the central nervous system symptoms of rotavirus: a qualitative review

A Hellysaz, M Hagbom - Viruses, 2021 - mdpi.com
This qualitative review on rotavirus infection and its complications in the central nervous
system (CNS) aims to understand the gut–brain mechanisms that give rise to CNS driven …

Molecular characterization identifies intra‐host recombination and zoonotic potential of canine rotavirus among dogs from Thailand

K Charoenkul, T Janetanakit… - Transboundary and …, 2021 - Wiley Online Library
Abstract From September 2016 to January 2019, we collected 710 rectal swabs from both
healthy and sick dogs from small animal hospitals in 5 provinces of Thailand. The samples …

Human genomics of the humoral immune response against polyomaviruses

F Hodel, AY Chong, P Scepanovic, ZM Xu… - Virus …, 2021 - academic.oup.com
Human polyomaviruses are widespread in humans and can cause severe disease in
immunocompromised individuals. To identify human genetic determinants of the humoral …