[HTML][HTML] Rac1, a potential target for tumor therapy
J Liang, L Oyang, S Rao, Y Han, X Luo, P Yi… - Frontiers in …, 2021 - frontiersin.org
RAS-related C3 botulinum toxin substrate 1 (Rac. 1) is one of the important members of Rho
GTPases. It is well known that Rac1 is a cytoskeleton regulation protein that regulates cell …
GTPases. It is well known that Rac1 is a cytoskeleton regulation protein that regulates cell …
Dietary bioactive diindolylmethane enhances the therapeutic efficacy of centchroman in breast cancer cells by regulating ABCB1/P-gp efflux transporter
Overexpression of drug efflux transporters is commonly associated with multidrug-resistance
in cancer therapy. Here for the first time, we investigated the ability of diindolylmethane …
in cancer therapy. Here for the first time, we investigated the ability of diindolylmethane …
Targeted delivery of doxorubicin through CD44 aptamer to cancer cells
Aim: The current investigation is focused on the targeted delivery of doxorubicin through
CD44 aptamer-mediated active targeting to the human breast cancer cells. Methods: CD44 …
CD44 aptamer-mediated active targeting to the human breast cancer cells. Methods: CD44 …
Dietary Piperine Suppresses Obesity-Associated Breast Cancer Growth and Metastasis by Regulating the miR-181c-3p/PPARα Axis
Adipocyte-derived leptin activates multiple oncogenic signaling, leading to breast cancer
cell progression and metastasis. Hence, finding effective strategies to inhibit the oncogenic …
cell progression and metastasis. Hence, finding effective strategies to inhibit the oncogenic …
Inhibitory effect of punicalagin on inflammatory and angiogenic activation of human umbilical vein endothelial cells
W Liu, Y Ou, Y Yang, X Zhang, L Huang… - Frontiers in …, 2021 - frontiersin.org
Punicalagin, a major ellagitannin isolated from pomegranate, is proved to have various
pharmacological activities with an undefined therapy mechanism. The objective of this …
pharmacological activities with an undefined therapy mechanism. The objective of this …
Knockout of Calcyclin Binding Protein Impedes the Growth of Breast Cancer Cells by Regulating Cell Apoptosis and β-Catenin Signaling
N Wang, Y Wang, H Wang, N Luo, W Yang… - DNA and Cell …, 2021 - liebertpub.com
Breast invasive carcinoma (BRCA) is becoming the most common malignant disease
worldwide, and there is intense interest in identifying diagnostic biomarkers that can be …
worldwide, and there is intense interest in identifying diagnostic biomarkers that can be …