Obesity predisposes individuals to the development of insulin resistance, which is a risk
factor for type 2 diabetes, and muscle plays a central role in this phenomenon. Insulin …

Mounting evidence suggests a role for mitochondrial dysfunction in the pathogenesis of
many diseases, including type 2 diabetes, aging, and ovarian failure. Because of the central …

Exercise training positively affects metabolic health through increased mitochondrial
oxidative capacity and improved glucose regulation and is the first line of treatment in …

Obesity is accompanied by numerous systemic and tissue-specific derangements, including
systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal …

Histone lysine crotonylation (Kcr) is a post-translational modification of histone proteins that
is involved in the regulation of gene transcription, acute and chronic kidney injury …

The modern lifestyle has a negative impact on health. It is usually accompanied by
increased stress levels and lower physical activity, which interferes with body homeostasis …

Context Patients with type 2 diabetes mellitus (T2DM) have elevated plasma branched-
chain amino acid (BCAA) levels. The underlying cause, however, is not known. Low …

Background Insulin resistance and impaired insulin secretion lead to disorders of glucose
metabolism, which contributes to the development of diabetes. Hydrogen sulfide (H2S), a …

This work synthesized the ceria oxide nanoparticles (CeO 2 NPs) using the plant extract of
Stachys japonica Miq and determined their antioxidant and antidiabetic activities. The …

Sedentary behavior constitutes a pandemic health threat contributing to the pathophysiology
of obesity and type 2 diabetes (T2D). Sedentarism is further associated with liver disease …