Multiple Sclerosis (MS) is a demyelinating disease of the human central nervous system
having an unconfirmed pathoetiology. Although animal models are used to mimic the …

The complement system is implicated in synapse loss in the MS hippocampus, but the
functional consequences of synapse loss remain poorly understood. Here, in post-mortem …

Multiple sclerosis (MS) is a demyelinating, autoimmune disease that affects a large number
of young adults. Novel therapies for MS are needed considering the efficiency and safety …

GFAP-IL6 transgenic mice are characterised by astroglial and microglial activation
predominantly in the cerebellum, hallmarks of many neuroinflammatory conditions …

Multiple sclerosis (MS) is a chronic and neurodegenerative disease of the central nervous
system (CNS) characterized by the immune mediated attack on axons and the subsequent …

This study aimed at testing the hypothesis that treatment with icariin (ICA, a type of flavonoid)
could mitigate the cuprizone (CPZ)-induced acute demyelination in the brain of mice and the …

Myelination is a fundamental molecular event within the vertebrate central nervous system
(CNS) where oligodendrocytes wrap around axons to form a myelin sheath which allows …

A change in visual perception is a frequent early symptom of multiple sclerosis (MS), the
pathoetiology of which remains unclear. Following a slow demyelination process caused by …