Reactive oxygen species (ROS), either derived from exogenous sources or overproduced
endogenously, can disrupt the body's antioxidant defenses leading to compromised redox …

Nuclear factor erythroid 2-related factor (Nrf2) is a transcriptional activator of the cell
protection gene that binds to the antioxidant response element (ARE). Therefore, Nrf2 …

Interleukin (IL)-25 is a cytokine released by airway epithelial cells responding to pathogens.
Excessive production of reactive oxygen species (ROS) leads to airway inflammation and …

We assessed the oxidative potential (OP) of both water-soluble and methanol-soluble
fractions of ambient fine particulate matter (PM 2.5) in the Midwestern United States. A large …

Asthma is an allergic chronic inflammatory disease of the pulmonary airways, characterized
by the infiltration of white blood cells and release of inflammatory cytokines of complex …

Acrylamide is a readily exposed toxic organic compound due to its formation in many
carbohydrate rich foods that are cooked at high temperatures. Excessive production of …

The prevalence of asthma is considerably high among women of childbearing age. Most
asthmatic women also often have other atopic disorders. Therefore, the differentiation …

Reactive oxygen species (ROS) are an important contributor to adverse health effects
associated with ambient air pollution. Despite infiltration of ROS from outdoors, and possible …

Oxidative stress is a hallmark of numerous airway diseases, contributing to extensive cell
and tissue damage. Cell membranes and the airway mucosal lining are rich in …

Objective Asthma inflammation may feature an imbalance between oxidative stress and
antioxidant defenses. Oxidative stress induces propagation of airways inflammation and …