A cross-population atlas of genetic associations for 220 human phenotypes

S Sakaue, M Kanai, Y Tanigawa, J Karjalainen… - Nature …, 2021 - nature.com
Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non …

Genetic profiles of 103,106 individuals in the Taiwan Biobank provide insights into the health and history of Han Chinese

CY Wei, JH Yang, EC Yeh, MF Tsai, HJ Kao… - NPJ genomic …, 2021 - nature.com
Personalized medical care focuses on prediction of disease risk and response to
medications. To build the risk models, access to both large-scale genomic resources and …

jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population

S Tadaka, E Hishinuma, S Komaki… - Nucleic acids …, 2021 - academic.oup.com
Abstract In the Tohoku Medical Megabank project, genome and omics analyses of
participants in two cohort studies were performed. A part of the data is available at the …

The Asian Pacific Association for the Study of the Liver clinical practice guidance: the diagnosis and management of patients with autoimmune hepatitis

G Wang, A Tanaka, H Zhao, J Jia, X Ma… - Hepatology …, 2021 - Springer
Guiqiang Wang1, 18· Atsushi Tanaka2· Hong Zhao1, 1 8· Jidong Jia3· Xiong Ma4· Kenichi
Harada5· Fu‑Sheng Wang6· Lai Wei7· Qixia Wang4· Ying Sun6· Yuan Hong1· Huiying …

Study profile of the tohoku medical megabank community-based cohort study

A Hozawa, K Tanno, N Nakaya, T Nakamura… - Journal of …, 2021 - jstage.jst.go.jp
Background: We established a community-based cohort study to assess the long-term
impact of the Great East Japan Earthquake on disaster victims and gene-environment …

Tsunami in the last 15 years: a bibliometric analysis with a detailed overview and future directions

N Jain, D Virmani, A Abraham - Natural Hazards, 2021 - Springer
In the last fifteen years, tsunami science has progressed at a rapid pace. Three major
tsunamis: The Indian Ocean in 2004, the 2011 Tohoku tsunami, and the 2018 Palu tsunami …

White blood cell count profiles in multiple sclerosis during attacks before the initiation of acute and chronic treatments

T Akaishi, T Misu, K Fujihara, N Nakaya… - Scientific Reports, 2021 - nature.com
Multiple sclerosis (MS) is a major demyelinating disease of the central nervous system;
however, its exact mechanism is unknown. This study aimed to elucidate the profile of white …

Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator

M Yamada, IN Motoike, K Kojima, N Fuse… - Communications …, 2021 - nature.com
Lung function reflects the ability of the respiratory system and is utilized for the assessment
of respiratory diseases. Because type 2 airway inflammation influences lung function …

[HTML][HTML] A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c

H Zempo, SJ Kim, N Fuku, Y Nishida, Y Higaki… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Abstract Type 2 Diabetes (T2D) is an emerging public health problem in Asia. Although
ethnic specific mtDNA polymorphisms have been shown to contribute to T2D risk, the …

Wide-targeted metabolome analysis identifies potential biomarkers for prognosis prediction of epithelial ovarian cancer

E Hishinuma, M Shimada, N Matsukawa, D Saigusa… - Toxins, 2021 - mdpi.com
Epithelial ovarian cancer (EOC) is a fatal gynecologic cancer, and its poor prognosis is
mainly due to delayed diagnosis. Therefore, biomarker identification and prognosis …