During the past decade, accumulating evidence from the research highlights the suggested
effects of bacterial communities of the human gut microbiota and their metabolites on health …

Many recent studies have shown that the gut microbiome plays important roles in human
physiology and pathology. Also, microbiome-based therapies have been used to improve …

Objective We aimed to determine whether fecal microbiota transplant (FMT) is safe and
possibly efficacious in treating constipation, motor, and non-motor symptoms in Parkinson's …

Coffee is one of the most popular beverages consumed worldwide. Roasted coffee is a
complex mixture of thousands of bioactive compounds, and some of them have numerous …

Parkinson's disease (PD) is a complicated neurodegenerative disease attributed to
multifactorial changes. However, its pathological mechanism remains undetermined …

Neuroinflammation is a key component of neurological disorders and is an important
therapeutic target; however, immunotherapies have been largely unsuccessful. In cases …

About 60 years ago, the discovery of a deficiency of dopamine in the nigro-striatal system
led to a variety of symptomatic therapeutic strategies to supplement dopamine and to …

Recently, the concept of the brain-gut-microbiota (BGM) axis disturbances in the
pathogenesis of Alzheimer's disease (AD) has been receiving growing attention. At the …

Parkinson's disease (PD) is a multifactorial neurodegenerative disorder that currently affects
1% of the population over the age of 60 years, and for which no disease-modifying …

Glutathione (GSH) is the most abundant intrinsic antioxidant in the central nervous system,
and its substrate cysteine readily becomes the oxidized dimeric cystine. Since neurons lack …