MAOA promotes prostate cancer cell perineural invasion through SEMA3C/PlexinA2/NRP1–cMET signaling

L Yin, J Li, J Wang, T Pu, J Wei, Q Li, BJ Wu - Oncogene, 2021 - nature.com
Perineural invasion (PNI), a pathologic feature defined as cancer cell invasion in, around,
and through nerves, is an indicator of poor prognosis and survival in prostate cancer (PC) …

[HTML][HTML] The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

T Okui, M Hiasa, S Ryumon, K Ono, Y Kunisada… - Journal of bone …, 2021 - Elsevier
Bone pain is a common complication of breast cancer (BC) bone metastasis and is a major
cause of increased morbidity and mortality. Although the mechanism of BC-associated bone …

Glucagon prevents cytotoxicity induced by methylglyoxal in a rat neuronal cell line model

MS Mohiuddin, T Himeno, Y Yamada, Y Morishita… - Biomolecules, 2021 - mdpi.com
Although diabetic polyneuropathy (DPN) is a frequent diabetic complication, no effective
therapeutic approach has been established. Glucagon is a crucial hormone for glucose …

The neurodynamic treatment induces biological changes in sensory and motor neurons in vitro

G Carta, G Gambarotta, BE Fornasari, L Muratori… - Scientific Reports, 2021 - nature.com
Nerves are subjected to tensile forces in various paradigms such as injury and regeneration,
joint movement, and rehabilitation treatments, as in the case of neurodynamic treatment …

In vitro effects of photobiomodulation therapy on 50B11 sensory neurons: evaluation of cell metabolism, oxidative stress, mitochondrial membrane potential (MMP) …

L Zupin, E Barbi, R Sagredini, G Ottaviani… - Journal of …, 2021 - Wiley Online Library
The analgesic properties of photobiomodulation therapy (PBMT) have been raising
increasing interest in the clinical community due to the positive effects observed on patients …

Development of EQ-6, a novel analogue of ethoxyquin to prevent chemotherapy-induced peripheral neuropathy

A Cetinkaya-Fisgin, J Zhu, X Luan, JS Kim, B Oh… - …, 2021 - Springer
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and often dose-limiting
side effect of many cancer drugs. Because the onset of neuronal injury is known, it is an …

Targeting alternative splicing as a novel approach to chemotherapy induced peripheral neuropathy

MN Swift - 2021 - eprints.nottingham.ac.uk
Chemotherapy induced peripheral neuropathy (CIPN) is one of the most prevalent adverse
effects of many chemotherapy drugs. It is estimated that up to 85% of patients suffer from …

Differentiation of the 50B11 dorsal root ganglion cells into NGF and GDNF responsive nociceptor subtypes

D Matusica, J Canlas, A Martin… - Molecular …, 2021 - researchnow.flinders.edu.au
The embryonic rat dorsal root ganglion (DRG) neuron-derived 50B11 cell line is a promising
sensory neuron model expressing markers characteristic of NGF and GDNF-dependent C …