Cell-based regenerative medicine for renovascular disease

LO Lerman - Trends in molecular medicine, 2021 - cell.com
Renal artery stenosis (RAS) elicits the development of hypertension and post-stenotic
kidney damage, which may become irresponsive to restoration of arterial patency. Rather …

Stem cell therapy for microvascular injury associated with ischemic nephropathy

SC Textor, A Abumoawad, A Saad, C Ferguson… - Cells, 2021 - mdpi.com
Ischemic nephropathy reflects progressive loss of kidney function due to large vessel
atherosclerotic occlusive disease. Recent studies indicate that this process is characterized …

Intrarenal modulation of NF-κB activity attenuates cardiac injury in a swine model of CKD: a renal-cardio axis

AR Chade, JE Engel, ME Hall, A Eirin… - American Journal of …, 2021 - journals.physiology.org
Patients with chronic kidney disease (CKD) have a high cardiovascular mortality. CKD and
heart failure (HF) coexist in up to 50% of patients, and both associate with inflammation. We …

Mesenchymal stem/stromal cell-derived extracellular vesicles elicit better preservation of the intra-renal microvasculature than renal revascularization in pigs with …

CM Ferguson, RA Farahani, XY Zhu, H Tang… - Cells, 2021 - mdpi.com
Background: Percutaneous transluminal renal angioplasty (PTRA) confers clinical and
mortality benefits in select 'high-risk'patients with renovascular disease (RVD). Intra-renal …

Magnetization transfer imaging predicts porcine kidney recovery after revascularization of renal artery stenosis

M Afarideh, K Jiang, CM Ferguson… - Investigative …, 2021 - journals.lww.com
Objectives Magnetization transfer imaging is a novel noninvasive tool for the detection of
kidney fibrosis, but its association with kidney function and hemodynamics is unclear …

Percutaneous transluminal renal angioplasty attenuates poststenotic kidney mitochondrial damage in pigs with renal artery stenosis and metabolic syndrome

RA Farahani, M Afarideh, XY Zhu… - Journal of cellular …, 2021 - Wiley Online Library
Percutaneous transluminal renal angioplasty (PTRA) has been used to treat renovascular
disease (RVD), a chronic condition characterized by renal ischemia and metabolic …

Ischemic Nephropaty: The Role of the Renal Artery Stenosis Revascularization on Renal Stem Cells

R Cianci, AM Perrotta, A Gigante, F Errigo, C Ferri… - Medicina, 2021 - mdpi.com
We report the case of a 65-year-old man with acute GFR decline to 37 mL/min and
uncontrolled high blood pressure. He was suspected for renovascular hypertension and …