From flies to men: ROS and the NADPH oxidase in phagocytes

ZM Moghadam, P Henneke, J Kolter - Frontiers in cell and …, 2021 - frontiersin.org
The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …

[HTML][HTML] Undiagnosed liver diseases

E Gao, J Hercun, T Heller… - Translational …, 2021 - ncbi.nlm.nih.gov
The landscape of chronic liver disease has drastically changed over the past 20 years,
largely due to advances in antiviral therapy and the rise of metabolic syndrome and …

Liver abscess in chronic granulomatous disease—two decades of experience from a tertiary care centre in North-West India

RK Pilania, A Rawat, P Vignesh, S Guleria… - Journal of Clinical …, 2021 - Springer
Purpose Most of the literature on liver abscess in chronic granulomatous disease (CGD)
emanates from developed countries. Data from developing countries are scarce. In this …

Anakinra for Treatment of Liver Abscesses in a Patient with a Novel CYBB Variant of Chronic Granulomatous Disease

C To, A Williams, L Droney - Journal of clinical immunology, 2021 - Springer
To the Editor, Chronic granulomatous disease (CGD) is a primary immunodeficiency
affecting phagocytes, caused by a defect in nicotinamide adenine dinucleotide phosphate …

Gut involvement in cellular immunodeficiencies

A Troilo, N Frede, C Della Bella, MM D'Elios - Cellular Primary …, 2021 - Springer
Primary cellular immunodeficiencies may often initially present with manifestations affecting
the gastrointestinal tract. Not only infections but also inflammatory, autoimmune, and in …

[HTML][HTML] Corticosteroid therapy for liver abscesses in a neonate with chronic granulomatous disease

A Darabi, G Mamouri, H Boskabadi, MS Sasan… - Journal of Pediatric …, 2021 - Elsevier
Chronic granulomatous disease (CGD) is a rare inherited immunodeficiency disorder,
characterized by susceptibility to recurrent infections, including hepatic abscess. These …

[PDF][PDF] and management of Budd‐Chiari syndrome

F Khan, MJ Armstrong, H Mehrzad, F Chen, D Neil… - academia.edu
Summary Background: Budd‐Chiari syndrome (BCS) is a rare but fatal disease caused by
obstruction in the hepatic venous outflow tract. Aim: To provide an update of the …

Chronic Granulomatous Disease

DE Arnold, JR Heimall - … and Secondary Immunodeficiency: A Case-Based …, 2021 - Springer
Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency due to
mutations in any of the critical subunits of the phagocyte NADPH oxidase complex, resulting …

Congenital Defects of Phagocytes

DJ Bogaert, F Haerynck - Cellular Primary Immunodeficiencies, 2021 - Springer
Phagocytes form the first line of defense against invading pathogens and play a key role in
wound healing following tissue injury. A broad range of monogenic defects affecting …