Status toward the implementation of precision dosing in children

JS Barrett, RF Barrett, AA Vinks - The Journal of Clinical …, 2021 - Wiley Online Library
Precision dosing is progressing beyond the conceptual and proof‐of‐concept stages toward
implementation. As the availability of dosing algorithms, tools, and platforms increases, so …

Does “birth” as an event impact maturation trajectory of renal clearance via glomerular filtration? Reexamining data in preterm and full‐term neonates by avoiding the …

F Salem, TN Johnson, ABJ Hodgkinson… - The Journal of …, 2021 - Wiley Online Library
Glomerular filtration rate (GFR) is an important measure of renal function. Various models for
its maturation have recently been compared; however, these have used markers, which are …

Population pharmacokinetics and dose optimization of vancomycin in neonates

SM Lee, S Yang, S Kang, MJ Chang - Scientific reports, 2021 - nature.com
The pharmacokinetics of vancomycin vary among neonates, and we aimed to conduct
population pharmacokinetic analysis to determine the optimal dosage of vancomycin in …

Determination of vancomycin exposure target and individualised dosing recommendations for neonates: model-informed precision dosing

Z Tang, J Guan, J Li, Y Yu, M Qian, J Cao… - International Journal of …, 2021 - Elsevier
Introduction Few studies incorporating population pharmacokinetic/pharmacodynamic (Pop-
PK/PD) modelling have been conducted to quantify the exposure target of vancomycin in …

Establishment of a population pharmacokinetics model of vancomycin in 94 infants with septicemia and its application in individualized therapy

Z Li, H Li, C Wang, Z Jiao, F Xu, H Sun - BMC Pharmacology and …, 2021 - Springer
Background We aim to develop a population pharmacokinetics (PopPK) model of
vancomycin for the treatment of septicemia in infants younger than one year. Factors …

Dose tailoring of vancomycin through population pharmacokinetic modeling among surgical patients in Pakistan

MM Munir, H Rasheed, MI Khokhar, RR Khan… - Frontiers in …, 2021 - frontiersin.org
Background: Vancomycin is a narrow therapeutic agent, and it is necessary to optimize the
dose to achieve safe therapeutic outcomes. The purpose of this study was to identify the …

[HTML][HTML] Терапевтический лекарственный мониторинг ванкомицина у новорожденных: проблемы и перспективы

БЕ Толкачев, ВИ Петров, ТЕ Заячникова… - Лечебное …, 2021 - cyberleninka.ru
Ванкомицин является одним из наиболее часто назначаемых антибиотиков для
лечения тяжелых нозокомиальных инфекций у новорожденных. Эмпирическое …

Vancomycin Treatment Management in Pediatric Patient Population

TH Tung - 2021 - hammer.purdue.edu
This research was to study the treatment and therapeutic drug monitoring of vancomycin,
one of the most prescribed antibiotics in pediatric intensive care units in US hospitals, from a …

[PDF][PDF] Vancomycin-Ototoxizität bei Frühgeborenen

JS Marißen - zhb.uni-luebeck.de
In Deutschland kommen jährlich mehr als 60.000 Frühgeborene–gemäß
Weltgesundheitsorganisation (WHO) als Geburt vor der vollendeten 37 …