The cerebral cortex is at the core of brain functions that are thought to be particularly
developed in the human species. Human cortex specificities stem from divergent features of …

Over the past few years, human-specific genes have received increasing attention as
potential major contributors responsible for the 3-fold difference in brain size between …

During embryonic development, neural stem/progenitor cells generate hundreds of different
cell types through the combination of intrinsic and extrinsic cues. Recent data obtained in …

Abstract Vacuolar protein sorting 41 (VPS41) is as part of the Homotypic fusion and Protein
Sorting (HOPS) complex required for lysosomal fusion events and, independent of HOPS …

Abstract Low-frequency 1q21. 1 distal deletion and duplication copy number variant (CNV)
carriers are predisposed to multiple neurodevelopmental disorders, including …

Eukaryotes have evolved a variety of mRNA surveillance mechanisms to detect and
degrade aberrant mRNAs with potential deleterious outcomes. Among them, nonsense …

Several copy number variants (CNVs) have been identified to confer high risk for a range of
neuropsychiatric conditions. Because of advances in genetic testing within clinical settings …

Within populations, some individuals tend to exhibit a bold or shy social behavior phenotype
relative to the mean. The neural underpinnings of these differing phenotypes–also …

The evolutionary expansion of the neocortex, the seat of higher cognitive functions in
humans, is primarily due to an increased and prolonged proliferation of neural progenitor …

Purpose This study aimed to explore the value of chromosomal microarray analysis (CMA)
and whole exome sequencing (WES) in the prenatal diagnosis of fetal isolated nasal bone …