Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches
Skin injuries and in particular, chronic wounds, are one of the major prevalent medical
problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration …
problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration …
[HTML][HTML] Development and application of endothelial cells derived from pluripotent stem cells in microphysiological systems models
CC Kennedy, EE Brown, NO Abutaleb… - Frontiers in …, 2021 - frontiersin.org
The vascular endothelium is present in all organs and blood vessels, facilitates the
exchange of nutrients and waste throughout different organ systems in the body, and sets …
exchange of nutrients and waste throughout different organ systems in the body, and sets …
Recent advances in the induced pluripotent stem cell‐based skin regeneration
S Choudhury, N Surendran… - Wound Repair and …, 2021 - Wiley Online Library
Skin regeneration has been a challenging clinical problem especially in cases of chronic
wounds such as diabetic foot ulcers, and epidermolysis bullosa‐related skin blisters …
wounds such as diabetic foot ulcers, and epidermolysis bullosa‐related skin blisters …
Silk Fibroin Scaffold Architecture Regulates Inflammatory Responses and Engraftment of Bone Marrow‐Mononuclear Cells
N Yang, MJ Moore, PL Michael… - Advanced …, 2021 - Wiley Online Library
Despite being one of the most clinically trialed cell therapies, bone marrow‐mononuclear
cell (BM‐MNC) infusion has largely failed to fulfill its clinical promise. Implanting biomimetic …
cell (BM‐MNC) infusion has largely failed to fulfill its clinical promise. Implanting biomimetic …
[HTML][HTML] Patient endothelial colony-forming cells to model coronary artery disease susceptibility and unravel the role of dysregulated mitochondrial redox signalling
Mechanisms involved in the individual susceptibility to atherosclerotic coronary artery
disease (CAD) beyond traditional risk factors are poorly understood. Here, we describe the …
disease (CAD) beyond traditional risk factors are poorly understood. Here, we describe the …
[HTML][HTML] TGF-β/Smad 信号通路在肝纤维化中的研究进展
韩道宁, 苏秀兰 - 生物医学转化, 2021 - swyxzh.ijournals.cn
摘要转化生长因子β (Transforming Growth Factor-β, TGF-β) 信号通路在调节细胞进程中起着至
关重要的作用. 就肝脏而言, TGF-β 信号通路贯穿肝脏疾病始终, 即从最初的肝细胞损伤到炎症 …
关重要的作用. 就肝脏而言, TGF-β 信号通路贯穿肝脏疾病始终, 即从最初的肝细胞损伤到炎症 …
VE-cadherin-based matrix promoting the self-reconstruction of pro-vascularization microenvironments and endothelial differentiation of human mesenchymal stem …
J Xie, X Li, Y Zhang, T Tang, G Chen, H Mao… - Journal of Materials …, 2021 - pubs.rsc.org
Regulating the secretion and endothelial differentiation of human mesenchymal stem cells
(hMSCs) plays an important role in the vascularization in tissue engineering and …
(hMSCs) plays an important role in the vascularization in tissue engineering and …
Therapeutic biomaterial approaches to alleviate chronic limb threatening ischemia
G Marsico, S Martin‐Saldaña, A Pandit - Advanced Science, 2021 - Wiley Online Library
Chronic limb threatening ischemia (CLTI) is a severe condition defined by the blockage of
arteries in the lower extremities that leads to the degeneration of blood vessels and is …
arteries in the lower extremities that leads to the degeneration of blood vessels and is …
Experimental study of fat derived pellets promoting wound healing in rats
L Zeng, S Zhou, C Chen, LH Zhou, X Shi, Z Wu… - …, 2021 - Taylor & Francis
To observe the effect of fat-derived pellets (FDP) on wound healing in rats, the inguinal fat of
rats was obtained, and the FDP were obtained after centrifugation. The cell activity and …
rats was obtained, and the FDP were obtained after centrifugation. The cell activity and …
[HTML][HTML] Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic properties
JD Hywood, S Sadeghipour, ZE Clayton, J Yuan… - Plos one, 2021 - journals.plos.org
Induced endothelial cells (iECs) generated from neonatal fibroblasts via transdifferentiation
have been shown to have pro-angiogenic properties and are a potential therapy for …
have been shown to have pro-angiogenic properties and are a potential therapy for …