Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure

J Trebicka, P Bork, A Krag, M Arumugam - … reviews Gastroenterology & …, 2021 - nature.com
The human gut microbiome has emerged as a major player in human health and disease.
The liver, as the first organ to encounter microbial products that cross the gut epithelial …

Role of microbiota-derived metabolites in alcoholic and non-alcoholic fatty liver diseases

JW Park, SE Kim, NY Lee, JH Kim, JH Jung… - International Journal of …, 2021 - mdpi.com
Chronic liver disease encompasses diseases that have various causes, such as alcoholic
liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). Gut microbiota …

Chronic liver diseases and the microbiome—translating our knowledge of gut microbiota to management of chronic liver disease

C Acharya, JS Bajaj - Gastroenterology, 2021 - Elsevier
Chronic liver disease is reaching epidemic proportions with the increasing prevalence of
obesity, nonalcoholic liver disease, and alcohol overuse worldwide. Most patients are not …

[HTML][HTML] Gut dysbiosis as a driver in alcohol-induced liver injury

B Fairfield, B Schnabl - Jhep Reports, 2021 - Elsevier
Alcohol-related liver disease characterises a broad spectrum of hepatic diseases that result
from heavy alcohol use, and include alcohol-related steatosis, steatohepatitis, fibrosis …

Propionate and butyrate produced by gut microbiota after probiotic supplementation attenuate lung metastasis of melanoma cells in mice

L Chen, X Zhou, Y Wang, D Wang… - Molecular Nutrition & …, 2021 - Wiley Online Library
Scope The beneficial effects of probiotics in reducing gastrointestinal inflammation and in
preventing colorectal cancer have been reported, but the mechanism underlying the …

A randomised placebo controlled trial of VSL#3® probiotic on biomarkers of cardiovascular risk and liver injury in non-alcoholic fatty liver disease

PL Chong, D Laight, RJ Aspinall, A Higginson… - BMC …, 2021 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is associated with increased
cardiovascular risk irrespective of conventional risk factors. The role of gut-liver interaction is …

[HTML][HTML] Tea polyphenols protect mice from acute ethanol-Induced liver injury by modulating the gut microbiota and short-chain fatty acids

Y Sun, K Kang, YL Li, LX Sang, B Chang - Journal of Functional Foods, 2021 - Elsevier
Tea polyphenols (TPs), naturally present in green tea, have a number of health benefits,
such as alleviating hepatic injury. Acute alcoholic liver injury was induced in C57BL/6 male …

The hepatic sinusoid in chronic liver disease: the optimal milieu for cancer

A Gibert-Ramos, D Sanfeliu-Redondo… - Cancers, 2021 - mdpi.com
Simple Summary During the development of chronic liver disease, the hepatic sinusoid
undergoes major changes that further compromise the hepatic function, inducing persistent …

Resveratrol butyrate esters inhibit BPA-induced liver damage in male offspring rats by modulating antioxidant capacity and gut microbiota

JX Liao, YW Chen, MK Shih, YL Tain, YT Yeh… - International Journal of …, 2021 - mdpi.com
Resveratrol can affect the physiology or biochemistry of offspring in the maternal–fetal
animal model. However, it exhibits low bioavailability in humans and animals. Fifteen-week …

Bile acids, liver cirrhosis, and extrahepatic vascular dysfunction

T Sauerbruch, M Hennenberg, J Trebicka… - Frontiers in …, 2021 - frontiersin.org
The bile acid pool with its individual bile acids (BA) is modulated in the enterohepatic
circulation by the liver as the primary site of synthesis, the motility of the gallbladder and of …