The steadfast advance of the synthetic biology field has enabled scientists to use genetically
engineered cells, instead of small molecules or biologics, as the basis for the development …

A fundamental challenge in synthetic biology is to create molecular circuits that can program
complex cellular functions. Because proteins can bind, cleave, and chemically modify one …

Background The concept of phase separation has been used to describe and interpret
physicochemical phenomena in biological systems for decades. Many intracellular …

Cell-specific targeting of therapeutics is a fundamental challenge in biomedicine. The use of
engineered proteins that interact with one another as designed, synthetic circuits represents …