Atherosclerosis is a multifactorial chronic inflammatory disease of the arterial wall, and an
important pathological basis of coronary heart disease. Endothelial cells, vascular smooth …

Atherosclerosis is the main cause of mortality in metabolic-related diseases, including
cardiovascular disease and type 2 diabetes (T2DM). Atherosclerosis is characterized by …

Atherosclerosis-caused cardiovascular diseases (CVD) are the leading cause of mortality in
type 2 diabetes mellitus (T2DM). Sodium-glucose cotransporter 2 (SGLT2) inhibitors are …

Atherothrombosis, a multifactorial and multistep artery disorder, represents one of the main
causes of morbidity and mortality worldwide. The development and progression of …

Atherosclerosis is a progressive insidious chronic disease that underlies most of the
cardiovascular pathologies, including myocardial infarction and ischemic stroke. The …

Aims Vascular smooth muscle cell (VSMC) phenotype shift is involved in the
pathophysiology of vascular injury or platelet-derived growth factor (PDGF)-induced …

Dysregulation of autophagy is an important underlying cause in the onset and progression
of many metabolic diseases, including diabetes. Studies in animal models and humans …

Proteolysis mediated by lysosomal cathepsin proteases maintains a physiological flow in
autophagy, phagocytosis and endocytosis. Neuronal Ceroid Lipofuscinosis (NCL) is a …

Dynamic remodeling of the actin cytoskeleton is an essential feature for virtually all actin-
dependent cellular processes, including cell migration, cell cycle progression, chromatin …

Atherosclerosis is a chronic inflammatory disease associated with lipid metabolism disorder.
Autophagy is a catabolic process and contributes to maintaining cellular homeostasis …