The highly contagious whooping cough agent Bordetella pertussis has evolved as a human-
restricted pathogen from a progenitor which also gave rise to Bordetella parapertussis and …

Whooping cough, or pertussis, is a highly communicable infectious disease caused by the
bacterium Bordetella pertussis. Vaccination once reduced the incidence of the disease, but …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

RTX leukotoxins are a diverse family of prokaryotic virulence factors that are secreted by the
type 1 secretion system (T1SS) and target leukocytes to subvert host defenses. T1SS …

Background Although pertussis cases globally have been controlled through the Expanded
Programme on Immunization (EPI), the incidence of pertussis has increased significantly in …

Background The prevalent resurgence of pertussis has recently become a critical public
health problem worldwide. To understand pertussis pathogenesis and the host response to …

Bordetella pertussis is a highly contagious bacterium that is the causative agent of whooping
cough (pertussis). Currently, acellular pertussis vaccines (aP, DTaP, and Tdap) are used to …

Despite the availability of a vaccine, pertussis is still a worldwide health problem. Outer
membrane vesicles (OMVs) in gram-negative bacteria can stimulate the immune system due …

Background The necessity of the tetanus-reduced dose diphtheria-acellular pertussis (Tdap)
vaccine in adolescence and adults has been emphasized since the resurgence of small …

Background: Pertussis is a current contagious bacterial disease caused by Bp. Given the
prevalence of pertussis, development of new vaccines is important. This study was …