[HTML][HTML] Resveratrol for cancer therapy: Challenges and future perspectives

B Ren, MXY Kwah, C Liu, Z Ma, MK Shanmugam… - Cancer letters, 2021 - Elsevier
Abstract Resveratrol (3, 4', 5-trihydroxy-trans-stilbene) has been expected to ameliorate
cancer and foster breakthroughs in cancer therapy. Despite thousands of preclinical studies …

Novel nanomedicines to overcome cancer multidrug resistance

Z Su, S Dong, SC Zhao, K Liu, Y Tan, X Jiang… - Drug Resistance …, 2021 - Elsevier
Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …

Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Mesoporous silica particles as drug delivery systems—the state of the art in loading methods and the recent progress in analytical techniques for monitoring these …

K Trzeciak, A Chotera-Ouda, II Bak-Sypien… - Pharmaceutics, 2021 - mdpi.com
Conventional administration of drugs is limited by poor water solubility, low permeability,
and mediocre targeting. Safe and effective delivery of drugs and therapeutic agents remains …

Cell-penetrating peptides (CPPs): An overview of applications for improving the potential of nanotherapeutics

K Desale, K Kuche, S Jain - Biomaterials Science, 2021 - pubs.rsc.org
In the field of nanotherapeutics, gaining cellular entry into the cytoplasm of the target cell
continues to be an ultimate challenge. There are many physicochemical factors such as …

Recent advances in nanocarriers for nutrient delivery

S Gorantla, G Wadhwa, S Jain, S Sankar… - Drug delivery and …, 2021 - Springer
For the past few years, there has been a surge in the use of nutraceuticals. The global
nutraceuticals market in 2020 was USD 417.66 billion, and the market value is expected to …

Innovative delivery systems loaded with plant bioactive ingredients: Formulation approaches and applications

A Kyriakoudi, E Spanidi, I Mourtzinos, K Gardikis - Plants, 2021 - mdpi.com
Plants constitute a rich source of diverse classes of valuable phytochemicals (eg, phenolic
acids, flavonoids, carotenoids, alkaloids) with proven biological activity (eg, antioxidant, anti …

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

TI Janjua, A Ahmed-Cox, AK Meka, FM Mansfeld… - Nanoscale, 2021 - pubs.rsc.org
The blood brain barrier (BBB) and blood tumour barrier (BTB) remain a major roadblock for
delivering therapies to treat brain cancer. Amongst brain cancers, glioblastoma (GBM) is …

Effect of sophorolipid on the curcumin-loaded ternary composite nanoparticles self-assembled from zein and chondroitin sulfate

Y Yuan, M Ma, S Zhang, C Liu, P Chen, H Li, D Wang… - Food …, 2021 - Elsevier
The curcumin (Cur) loaded ternary self-assembly composite nanoparticles consisting of
zein, chondroitin sulfate (CS) and sophorolipid (Spl) were designed successfully with zein-to …

Revisiting inorganic nanoparticles as promising therapeutic agents: A paradigm shift in oncological theranostics

MA Khan, D Singh, A Ahmad, HR Siddique - European Journal of …, 2021 - Elsevier
Cancer remains a global health problem largely due to a lack of effective therapies. Major
cancer management strategies include chemotherapy, surgical resection, and radiation …