[HTML][HTML] Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

[HTML][HTML] Consensus statement from the international consensus meeting on post-traumatic cranioplasty

C Iaccarino, A Kolias, PD Adelson, AM Rubiano… - Acta …, 2021 - Springer
Background Due to the lack of high-quality evidence which has hindered the development of
evidence-based guidelines, there is a need to provide general guidance on cranioplasty …

Preservation of brain activity in unresponsive patients identifies MCS star

A Thibaut, R Panda, J Annen, LRD Sanz… - Annals of …, 2021 - Wiley Online Library
Objective Brain‐injured patients who are unresponsive at the bedside (ie, vegetative
state/unresponsive wakefulness syndrome–VS/UWS) may present brain activity similar to …

[HTML][HTML] Narrative review: quantitative EEG in disorders of consciousness

B Wutzl, SM Golaszewski, K Leibnitz, PB Langthaler… - Brain Sciences, 2021 - mdpi.com
In this narrative review, we focus on the role of quantitative EEG technology in the diagnosis
and prognosis of patients with unresponsive wakefulness syndrome and minimally …

Research needs for prognostic modeling and trajectory analysis in patients with disorders of consciousness

FM Hammond, S Katta-Charles, MB Russell… - Neurocritical care, 2021 - Springer
Background The current state of the science regarding the care and prognosis of patients
with disorders of consciousness is limited. Scientific advances are needed to improve the …

What justifies the allocation of health care resources to patients with disorders of consciousness?

A Peterson, S Aas, D Wasserman - AJOB neuroscience, 2021 - Taylor & Francis
This paper critically engages ethical issues in the allocation of novel, and potentially costly,
health care resources to patients with disorders of consciousness. First, we review potential …

SECONDs administration guidelines: a fast tool to assess consciousness in brain-injured patients

LRD Sanz, C Aubinet, H Cassol, O Bodart… - JoVE (Journal of …, 2021 - jove.com
Establishing an accurate diagnosis is crucial for patients with disorders of consciousness
(DoC) following a severe brain injury. The Coma Recovery Scale-Revised (CRS-R) is the …

Resting-state NIRS–EEG in unresponsive patients with acute brain injury: A proof-of-concept study

MH Othman, M Bhattacharya, K Møller, S Kjeldsen… - Neurocritical Care, 2021 - Springer
Background Neurovascular-based imaging techniques such as functional MRI (fMRI) may
reveal signs of consciousness in clinically unresponsive patients but are often subject to …

[HTML][HTML] Early discrimination of cognitive motor dissociation from disorders of consciousness: pitfalls and clues

A Pincherle, F Rossi, J Jöhr, V Dunet, P Ryvlin… - Journal of …, 2021 - Springer
Bedside assessment of consciousness and awareness after a severe brain injury might be
hampered by confounding clinical factors (ie, pitfalls) interfering with the production of …

[HTML][HTML] Spontaneous eye blinking as a diagnostic marker in prolonged disorders of consciousness

A Magliacano, M Rosenfelder, N Hieber, A Bender… - Scientific Reports, 2021 - nature.com
Clinical diagnosis of patients with prolonged disorders of consciousness is very challenging.
As spontaneous eye blink rate (EBR) is reliably correlated with cognitive activity in healthy …