DNABERT: pre-trained Bidirectional Encoder Representations from Transformers model for DNA-language in genome
Motivation Deciphering the language of non-coding DNA is one of the fundamental
problems in genome research. Gene regulatory code is highly complex due to the existence …
problems in genome research. Gene regulatory code is highly complex due to the existence …
[HTML][HTML] Triangulating molecular evidence to prioritize candidate causal genes at established atopic dermatitis loci
GWASs for atopic dermatitis have identified 25 reproducible loci. We attempt to prioritize the
candidate causal genes at these loci using extensive molecular resources compiled into a …
candidate causal genes at these loci using extensive molecular resources compiled into a …
[HTML][HTML] Systematic Evaluation of DNA Sequence Variations on in vivo Transcription Factor Binding Affinity
The majority of the single nucleotide variants (SNVs) identified by genome-wide association
studies (GWAS) fall outside of the protein-coding regions. Elucidating the functional …
studies (GWAS) fall outside of the protein-coding regions. Elucidating the functional …
WEVar: a novel statistical learning framework for predicting noncoding regulatory variants
Understanding the functional consequence of noncoding variants is of great interest.
Though genome-wide association studies or quantitative trait locus analyses have identified …
Though genome-wide association studies or quantitative trait locus analyses have identified …
Modern Statistical Methods for Genetics and Genomic Studies
X Li - 2021 - search.proquest.com
Recent scientific advances in genetics and genomic studies have enabled the
characterization and prediction of functional genomic elements across the human genome …
characterization and prediction of functional genomic elements across the human genome …
Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome
Y Yao - 2021 - ir.library.oregonstate.edu
We describe a series of novel computational models, CERENKOV (Computational
Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2 …
Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2 …